Inhibitors | Comment | Organism | Structure |
---|---|---|---|
apocynin | blocks production of superoxide anion in sarcoplasmic reticulum of coronary arterial myocytes | Bos taurus | |
diphenylene iodonium | blocks production of superoxide anion in sarcoplasmic reticulum of coronary arterial myocytes | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
sarcoplasmic reticulum | local production of superoxide anion, which is increased by M1-receptor agonist, oxotremorine and Ca2+ ionophore, A23187, increased. Inhibitors diphenylene iodonium and apocynin, or superoxide dismutase and catalase, and subunit Nox4 siRNA all substantially block this local production of superoxide anion. Sarcoplasmic superoxide anion producing system is controlled by cADPR-RyR/Ca2+ signaling pathway | Bos taurus | 16529 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
myocyte | primary culture of coronary arterial myocyte | Bos taurus | - |