Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | when luminal NaCl in kidney is switched from 10 to 80 mM, a situation of initiating maximum tubuloglomerular feedback response, superoxide anion production significantly increases. In the presence of apocynin, superoxide anion production is inhibited by 80% | Oryctolagus cuniculus |
Application | Comment | Organism |
---|---|---|
medicine | in macula densa, increasing luminal NaCl induces superoxide anion production during tubuloglomerular feedback. Superoxide anion generated by the macula densa is primarily derived from NAD(P)H oxidase and is induced by depolarization | Oryctolagus cuniculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
apocynin | when luminal NaCl in kidney is switched from 10 to 80 mM, a situation of initiating maximum tubuloglomerular feedback response, superoxide anion production significantly increases. In the presence of apocynin, superoxide anion production is inhibited by 80% | Oryctolagus cuniculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Oryctolagus cuniculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | loop of Henle and macula densa | Oryctolagus cuniculus | - |