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Literature summary for 1.6.3.1 extracted from

  • Maia, L.; Vala, A.; Mira, L.
    NADH oxidase activity of rat liver xanthine dehydrogenase and xanthine oxidase-contribution for damage mechanisms (2005), Free Radic. Res., 39, 979-986.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADPH + O2 Rattus norvegicus in pathological conditions where an increase in NADH concentration occurs, the NADH oxidation catalysed by xanthine dehydrogenase may constitute an important pathway for reactive oxygen species-mediated tissue injuries NADP+ + O2-
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?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
enzymes xanthine oxidase and xanthine dehydrogenase catalyze NADH oxidation, generating superoxide radicals
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Source Tissue

Source Tissue Comment Organism Textmining
liver
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Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADPH + O2 in pathological conditions where an increase in NADH concentration occurs, the NADH oxidation catalysed by xanthine dehydrogenase may constitute an important pathway for reactive oxygen species-mediated tissue injuries Rattus norvegicus NADP+ + O2-
-
?
NADPH + O2 reaction catalyzed by xanthine oxidase and xanthine dehydrogenase Rattus norvegicus NADP+ + O2-
-
?