Literature summary for 1.6.3.1 extracted from

Harper, R.W.; Xu, C.; Eiserich, J.P.; Chen, Y.; Kao, C.Y.; Thai, P.; Setiadi, H.; Wu, R.
Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium (2005), FEBS Lett., 579, 4911-4917.

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Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	dual NADPH oxidases/peroxidases, Duox1 and Duox2. Regulation of expression by immunomodulatory Th1 and Th2 cytokines	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
tracheobronchial epithelial cell	primary tracheobronchial epithelial cell. Study on enzyme isoforms Duox1 and Duox2 mRNA expression after treatment with multiple cytokines. Duox1 expression is increased severalfold by treatment with Th2 cytokines IL-4 and IL-13, and by polyinosine-polycytydilic acid and rhinovirus infection. Duox2 expression is highly induced following treatment with Th1-cytokine IFN-gamma	Homo sapiens	-

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Release 2023.1 (January 2023)