Literature summary for 1.6.2.4 extracted from

Dhir, V.; Ivison, H.E.; Krone, N.; Shackleton, C.H.; Doherty, A.J.; Stewart, P.M.; Arlt, W.
Differential inhibition of CYP17A1 and CYP21A2 activities by the P450 oxidoreductase mutant A287P (2007), Mol. Endocrinol., 21, 1958-1968.

Search for more literature for 1.6.2.4

Protein Variants

Protein Variants	Comment	Organism
A287P	preferential inhibition of CYP17A1 over CYP21A2	Homo sapiens
H628P	mutation results in similar disruption of CYP17A1 and CYP21A2 activities	Homo sapiens
S244C	mutation results in similar disruption of CYP17A1 and CYP21A2 activities	Homo sapiens
Y181D	mutation results in similar disruption of CYP17A1 and CYP21A2 activities	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
P450 oxidoreductase	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)