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Literature summary for 1.6.2.4 extracted from

  • Bozcaarmutlu, A.
    Mechanism of inhibition of purified leaping mullet (Liza saliens) NADPH-cytochrome P450 reductase by toxic metals: aluminum and thallium (2007), J. Biochem. Mol. Toxicol., 21, 340-347.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
AlCl3 noncompetitive inhibitor, inhibitory effects of Al3+ and Tl3+ on purified cytochrome P450 reductase are partially recovered by 1 mM EDTA Chelon saliens
TlCl3 noncompetitive inhibitor, inhibitory effects of Al3+ and Tl3+ on purified cytochrome P450 reductase are partially recovered by 1 mM EDTA Chelon saliens

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Chelon saliens
-
-

Organism

Organism UniProt Comment Textmining
Chelon saliens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Chelon saliens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Chelon saliens
-

Synonyms

Synonyms Comment Organism
NADPH-cytochrome P450 reductase
-
Chelon saliens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0056
-
TlCl3
-
Chelon saliens
0.0089
-
AlCl3
-
Chelon saliens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.003
-
-
Chelon saliens TlCl3
0.034
-
-
Chelon saliens AlCl3