Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | CPR, the obligate electron donor for microsomal P450 enzymes, is essential for the bioactivation of many procarcinogens | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
a transgenic mouse model, with the NADPH-P450 reductase (Cpr) gene deleted in a lung-specific and doxycycline-inducible fashion (lung-Cpr-null) | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lung | the numbers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumors are reduced in the lung-Cpr-null mice but are increased in the liver-Cpr-null mice, relative to wild-type control mice | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | CPR, the obligate electron donor for microsomal P450 enzymes, is essential for the bioactivation of many procarcinogens | Mus musculus | ? | - |
? |