Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Cd2+ | 0.05 mM, 66% inhibition. IC50: 0.024 mM, noncompetitive inhibition; 0.05 mM, 66% inhibition, noncompetitive | Chelon saliens | |
Cr3+ | 0.05 mM,65% inhibition. IC50: 0.033 mM, noncompetitive inhibition; 0.05 mM, 65% inhibition, noncompetitive | Chelon saliens | |
Hg2+ | 0.05 mM, complete inhibition. IC50: 0.00007 mM, noncompetitive inhibition; 0.05 mM, complete inhibition, noncompetitive | Chelon saliens | |
additional information | no inhibition by 0.05 mM Zn2+ | Chelon saliens | |
Ni2+ | 0.05 mM, 37% inhibition. IC50: 0.143 mM, noncompetitive inhibition; 0.05 mM, 37% inhibition, noncompetitive | Chelon saliens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Chelon saliens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Chelon saliens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Chelon saliens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Chelon saliens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 ferricytochrome c + NADPH | - |
Chelon saliens | 2 ferrocytochrome c + NADP+ + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NADPH-cytochrome P450 reductase | - |
Chelon saliens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Chelon saliens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000048 | - |
Hg2+ | - |
Chelon saliens | |
0.000048 | - |
Hg2+ | pH 7.7, 24°C | Chelon saliens | |
0.0178 | - |
Cr3+ | pH 7.7, 24°C | Chelon saliens | |
0.018 | - |
Cr3+ | - |
Chelon saliens | |
0.0728 | - |
Cd2+ | pH 7.7, 24°C | Chelon saliens | |
0.073 | - |
Cd2+ | - |
Chelon saliens | |
0.329 | - |
Ni2+ | - |
Chelon saliens | |
0.329 | - |
Ni2+ | pH 7.7, 24°C | Chelon saliens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00007 | - |
0.05 mM, complete inhibition. IC50: 0.00007 mM, noncompetitive inhibition | Chelon saliens | Hg2+ | |
0.00007 | - |
pH 7.7, 24°C | Chelon saliens | Hg2+ | |
0.024 | - |
0.05 mM, 66% inhibition. IC50: 0.024 mM, noncompetitive inhibition | Chelon saliens | Cd2+ | |
0.024 | - |
pH 7.7, 24°C | Chelon saliens | Cr3+ | |
0.033 | - |
0.05 mM,65% inhibition. IC50: 0.033 mM, noncompetitive inhibition | Chelon saliens | Cr3+ | |
0.033 | - |
pH 7.7, 24°C | Chelon saliens | Cd2+ | |
0.143 | - |
0.05 mM, 37% inhibition. IC50: 0.143 mM, noncompetitive inhibition | Chelon saliens | Ni2+ | |
0.143 | - |
pH 7.7, 24°C | Chelon saliens | Ni2+ |