Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Mus musculus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + NAD+ | Mus musculus | - |
NADP+ + NADH | - |
? | |
NADPH + NAD+ | Mus musculus C57/BL6J | - |
NADP+ + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus C57/BL6J | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
NADPH + NAD+ | - |
Mus musculus | NADP+ + NADH | - |
? | |
NADPH + NAD+ | - |
Mus musculus C57/BL6J | NADP+ + NADH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
nicotinamide nucleotide transhydrogenase | - |
Mus musculus |
NNT | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | the absence of enzyme leads to variation in mitochondrial function and contributes to a unique mitochondrial redox phenotype that influences susceptibility to hypertension by contributing to endothelial and vascular dysfunction | Mus musculus |
physiological function | the enzyme activity impacts mitochondrial redox balance and the development of hypertension in mice | Mus musculus |