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Literature summary for 1.5.8.2 extracted from

  • Steenkamp, D.J.; Beinert, H.
    Mechanistic studies on the dehydrogenases of methylotrophic bacteria. 2. Kinetic studies on the intramolecular electron transfer in trimethylamine and dimethylamine dehydrogenase (1982), Biochem. J., 207, 241-252.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.5.8.2

Inhibitors

Inhibitors Comment Organism Structure
trimethylamine hyperbolic substrate inhibition Hyphomicrobium sp.
trimethylamine hyperbolic substrate inhibition Methylophilus methylotrophus

Metals/Ions

Metals/Ions Comment Organism Structure
Fe 4Fe-4S-center Methylophilus methylotrophus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus transfer of electrons to electron acceptors is mediated through the 4Fe-4S cluster dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
trimethylamine + H2O + electron transferring flavoprotein Hyphomicrobium sp. transfer of electrons to electron acceptors is mediated through the 4Fe-4S cluster dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
trimethylamine + H2O + electron transferring flavoprotein Methylophilus methylotrophus W3A1 transfer of electrons to electron acceptors is mediated through the 4Fe-4S cluster dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
trimethylamine + H2O + electron transferring flavoprotein Hyphomicrobium sp. X transfer of electrons to electron acceptors is mediated through the 4Fe-4S cluster dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Hyphomicrobium sp.
-
 Hyphomicrobium X
-
Methylophilus methylotrophus
-
-
-
Methylophilus methylotrophus W3A1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Methylophilus methylotrophus

Source Tissue

Source Tissue Comment Organism Textmining
cell culture
-
 Methylophilus methylotrophus
-
cell culture
-
 Hyphomicrobium sp.
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
trimethylamine + H2O + electron transferring flavoprotein transfer of electrons to electron acceptors is mediated through the 4Fe-4S cluster Methylophilus methylotrophus dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
trimethylamine + H2O + electron transferring flavoprotein transfer of electrons to electron acceptors is mediated through the 4Fe-4S cluster Hyphomicrobium sp. dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
trimethylamine + H2O + electron transferring flavoprotein transfer of electrons to electron acceptors is mediated through the 4Fe-4S cluster Methylophilus methylotrophus W3A1 dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?
trimethylamine + H2O + electron transferring flavoprotein transfer of electrons to electron acceptors is mediated through the 4Fe-4S cluster Hyphomicrobium sp. X dimethylamine + formaldehyde + reduced electron transferring flavoprotein
-
 ?

Cofactor

Cofactor Comment Organism Structure
electron transferring flavoprotein
-
 Methylophilus methylotrophus
electron transferring flavoprotein
-
 Hyphomicrobium sp.
FMN
-
 Methylophilus methylotrophus