Any feedback?
Literature summary for 1.5.5.2 extracted from
- L-proline dehydrogenases in hyperthermophilic archaea: distribution, function, structure, and application (2012), Appl. Microbiol. Biotechnol., 93, 83-93.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 4 | - |
L-proline | pH and temperature not specified in the publication | Pyrococcus horikoshii |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 42700 | - |
- |
Pyrococcus horikoshii |
| 55300 | - |
- |
Pyrococcus horikoshii |
| 440000 | - |
gel filtration | Pyrococcus horikoshii |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-proline + acceptor | Pyrococcus horikoshii | - |
(S)-1-pyrroline-5-carboxylate + reduced acceptor | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pyrococcus horikoshii | O59088 and O59089 | - |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.014 | - |
pH and temperature not specified in the publication | Pyrococcus horikoshii |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-proline + acceptor | - |
Pyrococcus horikoshii | (S)-1-pyrroline-5-carboxylate + reduced acceptor | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| heterooctamer | 4 * 55300 + 4 * 42700, calculated from amino acid sequence | Pyrococcus horikoshii |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| L-proline dehydrogenase | - |
Pyrococcus horikoshii |
| ProDH1 | - |
Pyrococcus horikoshii |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 90 | - |
the enzyme is stable for 120 min at 90°C | Pyrococcus horikoshii |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ATP | - |
Pyrococcus horikoshii | |
| FAD | - |
Pyrococcus horikoshii | |
| FMN | - |
Pyrococcus horikoshii | |
| [4Fe-4S]-center | - |
Pyrococcus horikoshii | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
