Activating Compound | Comment | Organism | Structure |
---|---|---|---|
2,6-dichlorophenolindophenol | the rate of the overall process is higher than with oxygen | Paenarthrobacter nicotinovorans | |
methylene blue | the rate of the overall process is higher than with oxygen | Paenarthrobacter nicotinovorans |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-6-hydroxynicotine + H2O + O2 | Paenarthrobacter nicotinovorans | - |
1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2 | - |
? | |
additional information | Paenarthrobacter nicotinovorans | enzyme production is induced by growing cells in D,L-nicotine as only source of carbon and nitrogen | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Paenarthrobacter nicotinovorans | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-6-hydroxynicotine + H2O + O2 | - |
Paenarthrobacter nicotinovorans | 1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2 | - |
? | |
(R)-6-hydroxynicotine + H2O + O2 | - |
Paenarthrobacter nicotinovorans | 1-(6-hydroxypyrid-3-yl)-4-(methylamino)-butan-1-one + H2O2 | transcient product is 6-hydroxy-N-methylmyosmine that hydrolyses spontaneously | ? | |
additional information | enzyme production is induced by growing cells in D,L-nicotine as only source of carbon and nitrogen | Paenarthrobacter nicotinovorans | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | - |
Paenarthrobacter nicotinovorans |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
19.8 | - |
6-hydroxy-D-nicotine | 30°C pH 9.2 | Paenarthrobacter nicotinovorans |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | one mol FAD per mol enzyme | Paenarthrobacter nicotinovorans | |
FAD | covalently bound to a histidine | Paenarthrobacter nicotinovorans |