Inhibitors | Comment | Organism | Structure |
---|---|---|---|
6,6'-[ethane-1,2-diyldi(piperidine-4,1-diyl)]bis[N-[(2-methoxyphenyl)methyl]hexan-1-amine] | 17fold selectivity for spermine oxidase over polyamine oxidase | Mus musculus | |
Chlorhexidine | - |
Mus musculus | |
methoctramine | 120fold selectivity for spermine oxidase over polyamine oxidase | Mus musculus | |
N1,N1'-(pentane-1,5-diyl)bis[N6-[(2-methoxyphenyl)methyl]hexane-1,6-diamine] | 9fold selectivity for spermine oxidase over polyamine oxidase | Mus musculus | |
N1,N7-bis(6-[[(2-methoxyphenyl)methyl]amino]hexyl)heptane-1,7-diamine | 40fold selectivity for spermine oxidase over polyamine oxidase | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000025 | - |
N1-[(naphthalen-2-yl)methyl]spermine | pH 7.5, 37°C | Mus musculus | |
0.000044 | - |
N1-[(thiophen-2-yl)methyl]spermine | pH 7.5, 37°C | Mus musculus | |
0.0002 | - |
N1-benzylspermine | pH 7.5, 37°C | Mus musculus | |
0.00052 | - |
N1-[(pyridin-2-yl)methyl]spermine | pH 7.5, 37°C | Mus musculus | |
0.001 | - |
N1-(3-[[(thiophen-2-yl)methyl]amino]propyl)octane-1,8-diamine | pH 7.5, 37°C | Mus musculus | |
0.025 | - |
N1-benzyldodecane-1,12-diamine | pH 7.5, 37°C | Mus musculus | |
0.06 | - |
3-[4-(3-aminopropoxy)butoxy]-N-benzylpropan-1-amine | pH 7.5, 37°C | Mus musculus | |
0.089 | - |
N1-[(thiophen-2-yl)methyl]dodecane-1,12-diamine | pH 7.5, 37°C | Mus musculus | |
0.382 | - |
N1-acetylspermine | pH 7.5, 37°C | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
peroxisome | - |
Mus musculus | 5777 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | Q8C0L6 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-[4-(3-aminopropoxy)butoxy]-N-benzylpropan-1-amine + O2 + H2O | - |
Mus musculus | ? | - |
? | |
N1-(3-[[(thiophen-2-yl)methyl]amino]propyl)octane-1,8-diamine + O2 + H2O | - |
Mus musculus | octane-1,8-diamine + N1-[(thiophen-2-yl)methyl]propanal + H2O2 | - |
? | |
N1-acetylspermine + O2 + H2O | - |
Mus musculus | spermidine + 3-acetamidopropanal + H2O2 | - |
? | |
N1-benzyldodecane-1,12-diamine + O2 + H2O | - |
Mus musculus | dodecane-1,12-diamine + N1-benzylpropanal + H2O2 | - |
? | |
N1-benzylspermine + O2 + H2O | - |
Mus musculus | spermidine + 3-(benzylamino)propanal + H2O2 | - |
? | |
N1-[(naphthalen-2-yl)methyl]spermine + O2 + H2O | - |
Mus musculus | spermidine + N1-[(naphthalen-2-yl)methyl]propanal + H2O2 | - |
? | |
N1-[(pyridin-2-yl)methyl]spermine + O2 + H2O | - |
Mus musculus | spermidine + N1-[(pyridin-2-yl)methyl]propanal + H2O2 | - |
? | |
N1-[(thiophen-2-yl)methyl]dodecane-1,12-diamine + O2 + H2O | - |
Mus musculus | ? | - |
? | |
N1-[(thiophen-2-yl)methyl]spermine + O2 + H2O | - |
Mus musculus | spermidine + N1-[(thiophen-2-yl)methyl]propanal + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PAOX | - |
Mus musculus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00001 | - |
methoctramine | pH 7.5, 37°C | Mus musculus | |
0.000047 | - |
N1,N7-bis(6-[[(2-methoxyphenyl)methyl]amino]hexyl)heptane-1,7-diamine | pH 7.5, 37°C | Mus musculus | |
0.00044 | - |
6,6'-[ethane-1,2-diyldi(piperidine-4,1-diyl)]bis[N-[(2-methoxyphenyl)methyl]hexan-1-amine] | pH 7.5, 37°C | Mus musculus | |
0.00053 | - |
N1,N1'-(pentane-1,5-diyl)bis[N6-[(2-methoxyphenyl)methyl]hexane-1,6-diamine] | pH 7.5, 37°C | Mus musculus | |
0.00125 | - |
Chlorhexidine | pH 7.5, 37°C | Mus musculus |