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Literature summary for 1.5.1.6 extracted from

  • Krupenko, N.I.; Dubard, M.E.; Strickland, K.C.; Moxley, K.M.; Oleinik, N.V.; Krupenko, S.A.
    ALDH1L2 is the mitochondrial homolog of 10-formyltetrahydrofolate dehydrogenase (2010), J. Biol. Chem., 285, 23056-23063.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.5.1.6

Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens
transfection of COS-7 and A-549 cells, and expression with green fluorescent protein fusion construct Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-
mitochondrion
-
 Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
130000
-
 x * 130000, green fluorescent protein fusion construct, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O75891
-
-
Homo sapiens Q3SY69
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification sequence contains a 22 amino acid N-terminal mitochondrial translocation signal Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain most highly expressed in pancreas, heart and brain Homo sapiens
-
heart most highly expressed in pancreas, heart and brain Homo sapiens
-
kidney
-
 Homo sapiens
-
kidney most highly expressed in pancreas, liver and kidney Homo sapiens
-
liver most highly expressed in pancreas, liver and kidney Homo sapiens
-
additional information cytosolic FDH mRNa is not detectable in cancer cells Homo sapiens
-
additional information In contrast to the cytosolic enzyme, mtFDH mRNA and protein are clearly present in cancer cell lines Homo sapiens
-
pancreas most highly expressed in pancreas, heart and brain Homo sapiens
-
pancreas most highly expressed in pancreas, liver and kidney Homo sapiens
-

Subunits

Subunits Comment Organism
? x * 130000, green fluorescent protein fusion construct, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
ALDH1L2
-
 Homo sapiens