Literature summary for 1.5.1.6 extracted from

Tsybovsky, Y.; Donato, H.; Krupenko, N.I.; Davies, C.; Krupenko, S.A.
Crystal structures of the carboxyl terminal domain of rat 10-formyltetrahydrofolate dehydrogenase: implications for the catalytic mechanism of aldehyde dehydrogenases (2007), Biochemistry, 46, 2917-2929.

Search for more literature for 1.5.1.6

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli	Rattus norvegicus

Crystallization (Commentary)

Crystallization (Comment)	Organism
C-terminal domain of FDH and its complexes with oxidized and reduced forms of NADP+ are crystallized using the hanging drop vapour diffusion method with 1.4-1.5 M ammonium sulfate and 0.1 M Tris-HCl, pH 7.0-7.5	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-NTA column chromatography	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
10-formyltetrahydrofolate + NADP+ + H2O	-	Rattus norvegicus	tetrahydrofolate + CO2 + NADPH + H+	-	?

Synonyms

Synonyms	Comment	Organism
10-formyltetrahydrofolate dehydrogenase	-	Rattus norvegicus
FDH	-	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
NADP+	dependent	Rattus norvegicus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)