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Literature summary for 1.5.1.6 extracted from

  • Kim, H.S.; Kim, J.M.; Roh, K.B.; Lee, H.H.; Kim, S.J.; Shin, Y.H.; Lee, B.L.
    Rat liver 10-formyltetrahydrofolate dehydrogenase, carbamoyl phosphate synthetase 1 and betaine homocysteine S-methytransferase were co-purified on Kunitz-type soybean trypsin inhibitor-coupled sepharose CL-4B (2007), J. Biochem. Mol. Biol., 40, 604-609.
    View publication on PubMed

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
90000
-
SDS-PAGE Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
co-purification with carbamoyl-phosphate synthetase 1 and betaine homocysteine S-methyltransferase using Kunitz-type soybean trypsin inhibitor-coupled Sepharose CL-4B column chromatography, Sephacryl S-200 gel filtration, and Superdex 200 gel filtration Rattus norvegicus
Kunitz-type soybean trypsin inhibitor-coupled Sepharose CL-4B column chromatography Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
10-formyltetrahydrofolate + NADP+ + H2O
-
Rattus norvegicus tetrahydrofolate + CO2 + NADPH + H+
-
?
ATP + formate + tetrahydrofolate
-
Rattus norvegicus ADP + phosphate + 10-formyltetrahydrofolate
-
?

Synonyms

Synonyms Comment Organism
10-formyltetrahydrofolate dehydrogenase
-
Rattus norvegicus
FDH
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
ATP
-
Rattus norvegicus
NADP+
-
Rattus norvegicus