Protein Variants | Comment | Organism |
---|---|---|
additional information | expression of constructs encompassing the full-length, just the catalytic and regulatory domain (amino acids 38-644), and encompassing the regulatory domain and part of the linker region (amino acids 348-656) | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(S)-SKI-72 | presence of (S)-SKI-72 leads to a Tm shift of approximately 10 degrees | Homo sapiens | |
S-adenosyl-L-methionine | presence of S-adenosyl-L-methionine leads to a Tm shift of about 4 degrees | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P42898 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
48 | - |
melting temperature | Homo sapiens |
53 | - |
melting temperature, presence of S-adenosyl-L-methionine | Homo sapiens |
58 | - |
melting temperature, presence of (S)-SKI-72 | Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00078 | - |
(S)-SKI-72 | pH not specified in the publication, temperature not specified in the publication | Homo sapiens | |
0.0058 | - |
S-adenosyl-L-methionine | pH not specified in the publication, temperature not specified in the publication | Homo sapiens |