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Literature summary for 1.5.1.5 extracted from

  • Sah, S.; Shah, R.; Govindan, A.; Varada, R.; Rex, K.; Varshney, U.
    Utilisation of 10-formyldihydrofolate as substrate by dihydrofolate reductase (DHFR) and 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR) tranformylase/IMP cyclohydrolase (PurH) in Escherichia coli (2018), Microbiology, 164, 982-991 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
22000
-
SDS-PAGE Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5,10-methylenetetrahydrofolate + NADP+ Escherichia coli the enzyme is involved in the folate recycling pathway 5,10-methenyltetrahydrofolate + NADPH + H+
-
?
5,10-methylenetetrahydrofolate + NADP+ Escherichia coli K12 the enzyme is involved in the folate recycling pathway 5,10-methenyltetrahydrofolate + NADPH + H+
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli P24186
-
-
Escherichia coli K12 P24186
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5,10-methylenetetrahydrofolate + NADP+
-
Escherichia coli 5,10-methenyltetrahydrofolate + NADPH + H+
-
?
5,10-methylenetetrahydrofolate + NADP+ the enzyme is involved in the folate recycling pathway Escherichia coli 5,10-methenyltetrahydrofolate + NADPH + H+
-
?
5,10-methylenetetrahydrofolate + NADP+
-
Escherichia coli K12 5,10-methenyltetrahydrofolate + NADPH + H+
-
?
5,10-methylenetetrahydrofolate + NADP+ the enzyme is involved in the folate recycling pathway Escherichia coli K12 5,10-methenyltetrahydrofolate + NADPH + H+
-
?

Subunits

Subunits Comment Organism
? x * 22000, SDS-PAGE Escherichia coli

Synonyms

Synonyms Comment Organism
FolD
-
Escherichia coli

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
assay at Escherichia coli

General Information

General Information Comment Organism
metabolism the enzyme is involved in the folate recycling pathway Escherichia coli