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Literature summary for 1.5.1.34 extracted from

  • Nakanishi, N.; Hasegawa, H.; Yamada, S.; Akino, M.
    Purification and physicochemical properties of NADPH-specific dihydropteridine reductase from bovine and human livers (1986), J. Biochem., 99, 635-644.
    View publication on PubMed
Search for more literature for 1.5.1.34

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 2 * 35000, NADPH-specific liver enzyme, SDS-PAGE Homo sapiens
35000
-
 2 * 35000, NADPH-specific liver enzyme, SDS-PAGE Bos taurus
65000
-
 equilibrium centrifugation, NADPH-specific liver enzyme Bos taurus
68000
-
 NADPH-specific enzyme, gel filtration Bos taurus
69000
-
 NADPH-specific liver enzyme, gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-
liver
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.706
-
 NADPH-specific liver enzyme Homo sapiens
0.972
-
 NADPH-specific liver enzyme Bos taurus

Subunits

Subunits Comment Organism
dimer 2 * 35000, NADPH-specific liver enzyme, SDS-PAGE Homo sapiens
dimer 2 * 35000, NADPH-specific liver enzyme, SDS-PAGE Bos taurus

Synonyms

Synonyms Comment Organism
More enzyme is not identical with dihydrofolate reductase Homo sapiens
More enzyme is not identical with dihydrofolate reductase Bos taurus
More NADPH-specific dihydropteridine reductase and NADH-dihydropteridine reductase have no common antigenic determinants, and show different physicochemical properties Homo sapiens
More NADPH-specific dihydropteridine reductase and NADH-dihydropteridine reductase have no common antigenic determinants, and show different physicochemical properties Bos taurus

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Homo sapiens
NADH liver: 2 distinct dihydropteridine reductases which catalyze the conversion of the quinonoid dihydropteridine to tetrahydropterin: NADH-dihydropteridine reductase, DPR, utilizes NADH as a better substrate than NADPH, NADPH-specific dihydropteridine reductase, TPR, shows strict specificity for NADPH Bos taurus
NADPH
-
 Homo sapiens
NADPH liver: 2 distinct dihydropteridine reductases which catalyze the conversion of the quinonoid dihydropteridine to tetrahydropterin: NADH-dihydropteridine reductase, DPR, utilizes NADH as a better substrate than NADPH, NADPH-specific dihydropteridine reductase, TPR, shows strict specificity for NADPH Bos taurus