BRENDA - Enzyme Database
show all sequences of 1.5.1.30

Characterization of the purified NADPH-flavin reductase of human erythrocytes

Yubisui, T.; Matsuki, T.; Takeshita, M.; Yoneyama, Y.; J. Biochem. 85, 719-728 (1979)

Data extracted from this reference:

General Stability
General Stability
Organism
freezing and thawing causes no appreciable loss of the enzyme activity
Homo sapiens
Inhibitors
Inhibitors
Commentary
Organism
Structure
1,10-phenanthroline
-
Homo sapiens
2,3-diphosphoglycerate
-
Homo sapiens
acrinol
-
Homo sapiens
Bathocuproine sulfonate
-
Homo sapiens
Cu2+
-
Homo sapiens
HgCl2
-
Homo sapiens
NADP+
0.1 mM, about 50% inhibition at no inhibition by NAD+ at pH 7.5, 12% inhibition at pH 4.8
Homo sapiens
PCMB
-
Homo sapiens
proflavin hemisulfate
-
Homo sapiens
SeO32-
-
Homo sapiens
Zn2+
-
Homo sapiens
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
additional information
Fe2+, Fe3+, Mg2+, and Ca2+ do not affect the enzyme activity
Homo sapiens
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
21500
-
x * 21500, SDS-PAGE
Homo sapiens
22000
-
gel filtration
Homo sapiens
Organism
Organism
UniProt
Commentary
Textmining
Homo sapiens
-
-
-
Purification (Commentary)
Purification (Commentary)
Organism
-
Homo sapiens
Source Tissue
Source Tissue
Commentary
Organism
Textmining
erythrocyte
-
Homo sapiens
-
Specific Activity [micromol/min/mg]
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.37
-
pH 7.0, 25°C
Homo sapiens
Storage Stability
Storage Stability
Organism
4°C, the purified enzyme is stable at
Homo sapiens
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
FMN + NADPH + H+
-
392188
Homo sapiens
FMNH2 + NADP+
-
-
-
?
Subunits
Subunits
Commentary
Organism
?
x * 21500, SDS-PAGE
Homo sapiens
Synonyms
Synonyms
Commentary
Organism
NADPH-FMN reductase
-
Homo sapiens
Temperature Stability [°C]
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
100
-
boiling of the enzyme leads to complete loss of the FMN reductase activity
Homo sapiens
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
4.8
-
-
Homo sapiens
pH Range
pH Minimum
pH Maximum
Commentary
Organism
4.5
8
pH 4.5: about 85% of maximal activity, pH 8.0: about 45% of maximal activity
Homo sapiens
Cofactor
Cofactor
Commentary
Organism
Structure
NADPH
the FMN reductase activity is highly specific for NADPH, and the activity with NADH is 10% of that with NADPH
Homo sapiens
pI Value
Organism
Commentary
pI Value Maximum
pI Value
Homo sapiens
-
-
8.1
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADPH
the FMN reductase activity is highly specific for NADPH, and the activity with NADH is 10% of that with NADPH
Homo sapiens
General Stability (protein specific)
General Stability
Organism
freezing and thawing causes no appreciable loss of the enzyme activity
Homo sapiens
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
1,10-phenanthroline
-
Homo sapiens
2,3-diphosphoglycerate
-
Homo sapiens
acrinol
-
Homo sapiens
Bathocuproine sulfonate
-
Homo sapiens
Cu2+
-
Homo sapiens
HgCl2
-
Homo sapiens
NADP+
0.1 mM, about 50% inhibition at no inhibition by NAD+ at pH 7.5, 12% inhibition at pH 4.8
Homo sapiens
PCMB
-
Homo sapiens
proflavin hemisulfate
-
Homo sapiens
SeO32-
-
Homo sapiens
Zn2+
-
Homo sapiens
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
additional information
Fe2+, Fe3+, Mg2+, and Ca2+ do not affect the enzyme activity
Homo sapiens
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
21500
-
x * 21500, SDS-PAGE
Homo sapiens
22000
-
gel filtration
Homo sapiens
Purification (Commentary) (protein specific)
Commentary
Organism
-
Homo sapiens
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
erythrocyte
-
Homo sapiens
-
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [µmol/min/mg]
Specific Activity Maximum [µmol/min/mg]
Commentary
Organism
0.37
-
pH 7.0, 25°C
Homo sapiens
Storage Stability (protein specific)
Storage Stability
Organism
4°C, the purified enzyme is stable at
Homo sapiens
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
FMN + NADPH + H+
-
392188
Homo sapiens
FMNH2 + NADP+
-
-
-
?
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 21500, SDS-PAGE
Homo sapiens
Temperature Stability [°C] (protein specific)
Temperature Stability Minimum [°C]
Temperature Stability Maximum [°C]
Commentary
Organism
100
-
boiling of the enzyme leads to complete loss of the FMN reductase activity
Homo sapiens
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
4.8
-
-
Homo sapiens
pH Range (protein specific)
pH Minimum
pH Maximum
Commentary
Organism
4.5
8
pH 4.5: about 85% of maximal activity, pH 8.0: about 45% of maximal activity
Homo sapiens
pI Value (protein specific)
Organism
Commentary
pI Value Maximum
pI Value
Homo sapiens
-
-
8.1
Other publictions for EC 1.5.1.30
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
743224
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1
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1
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2
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4
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7
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1
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8
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3
1
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2
1
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2
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1
2
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1
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2
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4
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1
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8
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1
-
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2
1
-
-
-
-
-
-
-
2
2
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1
-
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1
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4
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5
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1
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1
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1
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1
3
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1
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724343
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1
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5
-
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4
-
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5
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1
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1
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1
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1
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5
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4
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1
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1
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-
-
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4
-
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6
6
724769
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ChemMedChem
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-
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2
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1
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1
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1
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1
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-
725248
Kozmin
Role for CysJ flavin reductase ...
Escherichia coli
J. Bacteriol.
192
2026-2033
2010
-
-
-
-
-
-
-
-
-
-
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-
-
4
-
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2
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1
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1
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-
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2
2
-
-
-
698992
Campbell
Fre Is the Major Flavin Reduct ...
Escherichia coli
J. Biol. Chem.
284
8322-8328
2009
2
-
1
-
1
-
-
2
-
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1
2
-
6
-
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1
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4
1
3
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1
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1
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2
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1
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4
1
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-
-
1
1
-
2
2
699057
Takahashi
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Bacillus subtilis, Bacillus subtilis WU-S2B
J. Biosci. Bioeng.
107
38-41
2009
2
-
1
-
-
-
7
-
-
6
2
4
-
11
-
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1
-
-
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2
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26
1
2
1
1
1
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1
1
1
3
-
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2
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1
3
-
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7
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6
2
4
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1
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2
-
26
1
1
1
1
-
1
1
1
-
-
1
1
-
-
-
684711
Jawanda
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Vibrio harveyi
Arch. Biochem. Biophys.
472
51-57
2008
-
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1
-
1
-
-
2
-
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1
-
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4
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1
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1
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1
1
2
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2
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1
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1
1
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685230
Jawanda
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Vibrio harveyi
Biochemistry
47
368-377
2008
-
-
1
-
-
-
-
4
-
-
1
-
-
3
-
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1
-
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1
1
1
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2
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2
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1
2
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4
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1
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1
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-
1
1
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-
2
-
-
-
-
-
-
-
-
-
-
689388
Tu
Activity coupling and complex ...
Aliivibrio fischeri, Vibrio harveyi
Photochem. Photobiol. Sci.
7
183-188
2008
-
-
-
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4
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2
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4
2
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4
4
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684610
Liu
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76
1271-1279
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1
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2
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2
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6
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1
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689909
Vorontsov
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Shigella flexneri
Protein Sci.
16
2483-2490
2007
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1
1
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2
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2
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1
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2
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671610
Li
Activity coupling of Vibrio ha ...
Vibrio harveyi
Arch. Biochem. Biophys.
454
26-31
2006
-
-
-
-
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3
-
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4
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1
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1
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-
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1
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-
-
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-
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672105
Li
Thermodynamic analysis of the ...
Vibrio harveyi
Biochemistry
45
14781-14787
2006
-
-
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-
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4
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672184
Deller
Characterization of a thermost ...
Bacillus subtilis
Biochemistry
45
7083-7091
2006
-
-
-
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1
3
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2
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7
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1
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1
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2
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1
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3
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678187
Okai
Crystal structures of the shor ...
Sulfurisphaera tokodaii, Sulfurisphaera tokodaii 7
Biochemistry
45
5103-5110
2006
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1
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16
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1
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1
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1
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657786
Gao
Altered mechanism of the alkan ...
Escherichia coli
Biochem. Biophys. Res. Commun.
331
1137-1145
2005
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2
3
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2
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1
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3
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1
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2
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-
-
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658108
Lei
Redox potential and equilibria ...
Aliivibrio fischeri, Vibrio harveyi
Biochemistry
44
261-267
2005
-
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2
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1
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-
2
-
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-
-
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7
-
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2
-
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-
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2
2
5
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2
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4
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2
4
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1
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2
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2
2
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2
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671139
Gao
Crystallization and preliminar ...
Escherichia coli
Acta Crystallogr. Sect. F
F61
837-840
2005
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1
1
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1
1
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659261
Kwasnicka
Coordinate expression of NADPH ...
Caenorhabditis elegans, Homo sapiens
J. Biol. Chem.
278
39051-39058
2003
2
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660061
Low
Energy transfer evidence for i ...
Vibrio harveyi
Photochem. Photobiol.
77
446-452
2003
-
-
1
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-
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-
2
-
-
1
2
-
4
-
-
1
1
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4
1
1
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-
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1
-
-
-
-
-
-
-
-
-
392205
Tang
Flavin specificity and subunit ...
Aliivibrio fischeri
Arch. Biochem. Biophys.
392
110-116
2001
-
-
-
-
-
-
-
-
-
-
-
1
-
5
-
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3
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-
-
-
392304
Matsubara
Purification, characterization ...
Rhodococcus erythropolis, Rhodococcus erythropolis D1
Appl. Environ. Microbiol.
67
1179-1184
2001
-
-
1
-
-
1
6
2
-
-
2
-
-
11
-
-
1
-
-
-
2
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4
1
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6
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2
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4
1
1
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1
-
1
-
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-
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-
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-
392303
Wang
Vibrio harveyi NADPH-FMN oxido ...
Vibrio harveyi
Biochemistry
39
7813-7819
2000
-
-
1
-
1
-
-
4
-
-
-
-
-
5
-
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2
-
-
-
-
-
-
-
-
-
-
714077
Cunningham
Initial-rate kinetics of the f ...
Homo sapiens
Biochem. J.
345
393-399
2000
-
-
-
-
-
-
2
3
-
-
-
-
-
3
-
-
-
-
-
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-
1
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-
3
2
-
-
-
-
-
-
-
3
3
392302
Zenno
Purification and characterizat ...
Bacillus subtilis, Bacillus subtilis ISW 1214.
Biosci. Biotechnol. Biochem.
62
1978-1987
1998
-
-
1
-
-
-
-
4
-
-
2
-
-
9
-
-
1
-
-
-
1
-
4
1
-
1
-
-
-
-
-
-
2
-
-
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-
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4
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-
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1
-
4
1
1
-
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-
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-
-
-
-
-
-
-
-
-
742109
Zenno
Purification and characetriza ...
Bacillus subtilis, Bacillus subtilis ISW 1214
Biosci. Biotechnol. Biochem.
62
1978-1987
1998
-
-
1
-
-
-
-
3
-
-
1
8
-
9
-
-
1
1
-
-
1
-
10
1
6
1
-
-
-
1
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-
3
-
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1
3
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3
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1
8
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1
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1
-
10
1
1
-
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-
1
-
-
-
-
1
1
-
-
-
392300
Liu
Vibrio harveyi NADPH:FMN oxido ...
Vibrio harveyi
Arch. Biochem. Biophys.
337
89-95
1997
-
-
-
-
-
-
-
5
-
-
1
1
-
4
-
-
1
-
-
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3
1
1
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3
1
-
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-
-
-
-
-
-
-
-
-
-
392301
Parry
An NADPH:FAD oxidoreductase fr ...
Streptomyces viridifaciens
J. Biol. Chem.
272
23303-23311
1997
-
-
1
-
-
-
-
4
-
-
3
1
-
5
-
-
1
-
-
-
2
-
3
1
1
1
-
-
4
-
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1
-
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1
1
-
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4
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1
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1
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2
-
3
1
1
-
-
4
-
-
-
-
-
-
-
-
-
-
392299
Tanner
Flavin reductase P: structure ...
Vibrio harveyi
Biochemistry
35
13531-13539
1996
-
-
1
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
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1
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-
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-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
714076
Shalloe
Evidence that biliverdin-IX be ...
Bos taurus
Biochem. J.
316
385-387
1996
-
-
-
-
-
-
-
-
-
-
-
-
-
5
-
-
1
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1
-
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-
-
-
-
-
-
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-
-
-
-
392298
Mack
Myocardial flavin reductase an ...
Oryctolagus cuniculus
Biochem. Biophys. Res. Commun.
212
35-40
1995
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
6
-
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6
-
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-
-
-
-
-
-
392297
Lei
Vibrio harveyi NADPH-flavin ox ...
Vibrio harveyi, Vibrio harveyi MAV / ATCC 33843
J. Bacteriol.
176
3552-3558
1994
-
-
1
-
-
-
-
2
-
-
3
-
-
7
-
-
1
-
-
-
1
-
2
1
1
1
-
-
1
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
2
-
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3
-
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1
-
-
1
-
2
1
1
-
-
1
-
-
-
-
-
-
-
-
-
-
714010
Chikuba
Cloning and nucleotide sequenc ...
Homo sapiens
Biochem. Biophys. Res. Commun.
198
1170-1176
1994
-
-
1
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
4
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
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-
-
1
-
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-
-
-
-
-
-
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-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
714074
Yubisui
Characterization of a second f ...
Homo sapiens
Biochem. Int.
15
1-8
1987
-
-
-
-
-
-
-
2
-
-
1
-
-
6
-
-
1
-
-
3
-
-
5
1
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
2
-
-
1
-
-
-
-
1
-
3
-
-
5
1
-
-
-
-
1
-
-
1
-
-
-
-
-
-
392296
Lo
Purification and properties of ...
Entamoeba histolytica, Entamoeba histolytica NIH:200
Mol. Biochem. Parasitol.
2
23-30
1980
-
-
-
-
-
-
-
5
-
-
1
2
-
5
-
-
1
-
-
-
1
-
8
1
1
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
5
-
-
1
2
-
-
-
1
-
-
1
-
8
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
392188
Yubisui
Characterization of the purifi ...
Homo sapiens
J. Biochem.
85
719-728
1979
-
-
-
-
-
1
11
-
-
1
2
-
-
3
-
-
1
-
-
2
1
1
1
1
1
-
-
1
-
1
1
-
1
-
1
-
-
-
-
1
-
-
1
-
11
-
-
-
1
2
-
-
-
-
1
-
2
1
1
1
1
-
-
1
-
1
1
-
1
-
-
-
-
-
-