Crystallization (Comment) | Organism |
---|---|
structure of plasmid-encoded R67 isoform bound to NADP+, at 1.15 A resolution. NADP+ assumes an extended conformation with the nicotinamide ring bound near the center of the active site pore, the ribose and diphospate group extending toward the outer pore. the ribonicotinamide exhibits anti conformation, and the coenzyme displayes symmetrical binding mode with several water-mediated hydrogen bonds | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P00383 | plasmid-encoded R67 isoform | - |
Synonyms | Comment | Organism |
---|---|---|
R67 dihydrofolate reductase | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Escherichia coli |