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Literature summary for 1.5.1.3 extracted from

  • Anderson, D.D.; Woeller, C.F.; Stover, P.J.
    Small ubiquitin-like modifier-1 (SUMO-1) modification of thymidylate synthase and dihydrofolate reductase (2007), Clin. Chem. Lab. Med., 45, 1760-1763.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in BL21 cell Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
22000
-
x * 22000, SDS-PAGE of native enzyme. x * 42000, SDS-PAGE of enzyme modified by small ubiquitin-like modifier 1 Homo sapiens
42000
-
x * 22000, SDS-PAGE of native enzyme. x * 42000, SDS-PAGE of enzyme modified by small ubiquitin-like modifier 1 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P00374
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information both dihydrolfolate reductase and thymidylate synthase are substrates for UBC9-catalyzed modification with small ubiquitin-like modifier-1 Homo sapiens ?
-
?

Subunits

Subunits Comment Organism
? x * 22000, SDS-PAGE of native enzyme. x * 42000, SDS-PAGE of enzyme modified by small ubiquitin-like modifier 1 Homo sapiens