Literature summary for 1.5.1.3 extracted from

Stanley, B.G.; Neal, G.E.; Williams, D.C.
Dihydrofolic reductase (5,6,7,8-tetrahydrofolate:NADP oxidoreductase, EC 1.5.1.3) (1971), Methods Enzymol., 18B, 775-779.

No PubMed abstract available

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	enzyme assay	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
7,8-dihydrofolate + NADPH	at neutral pH the forward reaction is favored	Rattus norvegicus	5,6,7,8-tetrahydrofolate + NADP+	-	r
7,8-dihydrofolate + NADPH	equilibrium strongly favors tetrahydrofolate production	Rattus norvegicus	5,6,7,8-tetrahydrofolate + NADP+	-	r
additional information	assay method development	Rattus norvegicus	?	-	?

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Release 2023.1 (January 2023)