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Literature summary for 1.5.1.22 extracted from

  • Dando, P.R.
    Strombine [N-(carboxymethyl)-D-alanine]dehydrogenase and alanopine [meso-N-(1-carboxyethyl)-alanine]dehydrogenase from the mussel Mytilus edulis L. (1981), Biochem. Soc. Trans., 9, 297-298.
No PubMed abstract available

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
40
-
L-Ala Gly Mytilus edulis

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Mytilus edulis 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
38200
-
gel filtration Mytilus edulis

Organism

Organism UniProt Comment Textmining
Mytilus edulis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Mytilus edulis

Source Tissue

Source Tissue Comment Organism Textmining
adductor
-
Mytilus edulis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Gly + pyruvate + NADH r Mytilus edulis D-Strombine + NAD+ + H2O
-
?
L-Ala + pyruvate + NADH r Mytilus edulis meso-Alanopine + NAD+ + H2O
-
?
L-Ala + pyruvate + NADH in the reverse reaction: 81% of the activity with meso-alanopine compared to strombine Mytilus edulis meso-Alanopine + NAD+ + H2O
-
?
L-Met + pyruvate + NADH 3.7% of the activity with Gly Mytilus edulis ?
-
?
L-Ser + pyruvate + NADH 31% of the activity with Gly Mytilus edulis ?
-
?
L-Thr + pyruvate + NADH 3.7% of the activity with Gly Mytilus edulis ?
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
with Gly and pyruvate as substrates Mytilus edulis
9
-
with strombine as substrate Mytilus edulis

Cofactor

Cofactor Comment Organism Structure
NAD+ no activity with NADP+ Mytilus edulis
NADH no activity with NADPH Mytilus edulis