Literature summary for 1.5.1.20 extracted from

Chiang, E.P.; Wang, Y.C.; Tang, F.Y.
Folate restriction and methylenetetrahydrofolate reductase 677T polymorphism decreases adoMet synthesis via folate-dependent remethylation in human-transformed lymphoblasts (2007), Leukemia, 21, 651-658.

Search for more literature for 1.5.1.20

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Epstein-Barr virus-transformed lymphoblasts	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	the homozygous mutation (677TT) of the gene polymorphism C677T reduces enzyme activity, alters cellular folate composition, and decreases S-adenosyl methionine synthesis via folate-dependent re-methylation	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Synonyms

Synonyms	Comment	Organism
methylenetetrahydrofolate reductase	-	Homo sapiens
MTHFR	-	Homo sapiens

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Release 2023.1 (January 2023)