Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | increased activity of alanopine dehydrogenase, ADH, and strombine dehydrogenase, SDH, enzymes in Montipora capitata exposed to prolonged durations of hypoxic conditions | Montipora capitata |
Application | Comment | Organism |
---|---|---|
diagnostics | the significant positive relationship between exposure length and enzyme activity of ADH and strombine dehydrogenase, SDH, in Montipora capitata supports the implementation of these enzymes as biomarkers for rapid analysis of hypoxia-induced stress in corals | Montipora capitata |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alanine + pyruvate + NADH + H+ | Montipora capitata | - |
2,2'-iminodipropanoate + NAD+ + H2O | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Montipora capitata | - |
from Hawaii | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
coral nubbin | - |
Montipora capitata | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-alanine + pyruvate + NADH + H+ | - |
Montipora capitata | 2,2'-iminodipropanoate + NAD+ + H2O | - |
r |
Synonyms | Comment | Organism |
---|---|---|
ADH | - |
Montipora capitata |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
28 | - |
assay at | Montipora capitata |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Montipora capitata |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Montipora capitata | |
NADH | - |
Montipora capitata |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme activities of opine dehydrogenases, including alanopine dehydrogenase, are increased during anaerobic metabolism in corals under prolonged oxygen deprivation, due to invasive algal overgrowth and oxygen deprivation of wide-spread distributed Montipora capitata in Kaneohe Bay, Oahu, Hawaii | Montipora capitata |
additional information | enzyme ADH activity varies significantly with respect to hypoxia treatment type, treatment duration, and interaction between treatment duration and type. The combinatory effect of oxygen deprivation over time had no significant effect on ADH activity. Importantly, control and tank samples display no significant differences over 3 h, 6 h, 1 day, and 3 day times sets, indicating that bubbling within small chambers has no effect on target enzyme activity | Montipora capitata |
physiological function | enzyme ADH acts as one of the primary and anaerobic metabolic responses pathways during hypoxia. Montipora capitata increasingly relies upon alanopine dehydrogenase, ADH, and strombine dehydrogenase, SDH, for anaerobic catabolism under low-oxygen conditions | Montipora capitata |