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Literature summary for 1.4.3.4 extracted from

  • Manley-King, C.I.; TerreBlanche, G.; Castagnoli, N.; Bergh, J.J.; Petzer, J.P.
    Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides (2009), Bioorg. Med. Chem., 17, 3104-3110.
    View publication on PubMed
Search for more literature for 1.4.3.4

Inhibitors

Inhibitors Comment Organism Structure
1-methoxy-3-(3-methylphenyl)pyrrole
-
 Papio sp.
1-methyl-3-(3-bromophenyl)pyrrole
-
 Papio sp.
1-methyl-3-(3-chlorophenyl)pyrrole
-
 Papio sp.
1-methyl-3-(3-fluorophenyl)pyrrole
-
 Papio sp.
1-methyl-3-(3-methylphenyl)pyrrole
-
 Papio sp.
1-methyl-3-(3-trifluoromethylphenyl)pyrrole
-
 Papio sp.
1-methyl-3-phenylpyrrole
-
 Papio sp.
7-(3-chlorobenzyloxy)-4-formylcoumarin
-
 Papio sp.
isatin
-
 Papio sp.
N-methoxy-2-(3-methylphenyl)maleimide
-
 Papio sp.
N-methyl-2-(3-bromophenyl)maleimide
-
 Papio sp.
N-methyl-2-(3-chlorophenyl)maleimide
-
 Papio sp.
N-methyl-2-(3-fluorophenyl)maleimide
-
 Papio sp.
N-methyl-2-(3-methylphenyl)maleimide
-
 Papio sp.
N-methyl-2-(3-trifluoromethylphenyl)maleimide
-
 Papio sp.
N-methyl-2-phenylmaleimide
-
 Papio sp.
safinamide
-
 Papio sp.

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Papio sp. 5739
-

Organism

Organism UniProt Comment Textmining
Papio sp.
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Papio sp.
-

Synonyms

Synonyms Comment Organism
MAO-B
-
 Papio sp.
monoamine oxidase B
-
 Papio sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Papio sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Papio sp.

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00349
-
 N-methyl-2-phenylmaleimide pH 7.4, 37°C Papio sp.
0.00573
-
 N-methyl-2-(3-fluorophenyl)maleimide pH 7.4, 37°C Papio sp.
0.0066
-
 1-methyl-3-(3-trifluoromethylphenyl)pyrrole pH 7.4, 37°C Papio sp.
0.00666
-
 N-methyl-2-(3-chlorophenyl)maleimide pH 7.4, 37°C Papio sp.
0.00699
-
 N-methyl-2-(3-bromophenyl)maleimide pH 7.4, 37°C Papio sp.
0.00856
-
 N-methoxy-2-(3-methylphenyl)maleimide pH 7.4, 37°C Papio sp.
0.011
-
 N-methyl-2-(3-trifluoromethylphenyl)maleimide pH 7.4, 37°C Papio sp.
0.0143
-
 1-methyl-3-(3-bromophenyl)pyrrole pH 7.4, 37°C Papio sp.
0.0209
-
 1-methyl-3-(3-chlorophenyl)pyrrole pH 7.4, 37°C Papio sp.
0.0389
-
 1-methyl-3-(3-fluorophenyl)pyrrole pH 7.4, 37°C Papio sp.
0.0417
-
 1-methoxy-3-(3-methylphenyl)pyrrole pH 7.4, 37°C Papio sp.
0.056
-
 1-methyl-3-(3-methylphenyl)pyrrole pH 7.4, 37°C Papio sp.
0.086
-
 N-methyl-2-(3-methylphenyl)maleimide pH 7.4, 37°C Papio sp.
0.118
-
 1-methyl-3-phenylpyrrole pH 7.4, 37°C Papio sp.