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Literature summary for 1.4.3.3 extracted from

  • Konno, R.; Okamura, T.; Kasai, N.; Summer, K.H.; Niwa, A.
    Mutant rat strain lacking D-amino-acid oxidase (2009), Amino Acids, 37, 367-375.
    View publication on PubMed
Search for more literature for 1.4.3.3

Cloned(Commentary)

Cloned (Comment) Organism
expression in COS-1, NRK-52E and CCL-PK1 cells Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
additional information construction of a mutant rat strain LEA/SENDAI lacking D-amino-acid oxidase Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a D-amino acid + H2O + O2 Rattus norvegicus D-amino-acid oxidase catalyzes the oxidative deamination of D-amino acids, stereoisomers of the naturally occurring L-amino acids a 2-oxo acid + NH3 + H2O2
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 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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 male F344 Fischer, Wistar, and Sprague-Dawley rats
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Source Tissue

Source Tissue Comment Organism Textmining
kidney
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 Rattus norvegicus
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additional information tissue-specific enzyme expression, overview Rattus norvegicus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0082
-
 activity in F344 Fischer rat kidney Rattus norvegicus
0.0106
-
 activity in Sprague-Dawley rat kidney Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a D-amino acid + H2O + O2
-
 Rattus norvegicus a 2-oxo acid + NH3 + H2O2
-
 ?
a D-amino acid + H2O + O2 D-amino-acid oxidase catalyzes the oxidative deamination of D-amino acids, stereoisomers of the naturally occurring L-amino acids Rattus norvegicus a 2-oxo acid + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
DAO
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 Rattus norvegicus