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Literature summary for 1.4.3.22 extracted from

  • Pietrangeli, P.; Nocera, S.; Federico, R.; Mondovi, B.; Morpurgo, L.
    Inactivation of copper-containing amine oxidases by turnover products (2004), Eur. J. Biochem., 271, 146-152.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
H2O2 inactivation by turnover products is a slow reaction of the reduced protein with H2O2 subsequent to turnover and occurs in a similar way for all amines Lathyrus cicera

Organism

Organism UniProt Comment Textmining
Lathyrus cicera
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Lathyrus cicera

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
70
-
-
Lathyrus cicera

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-aminomethylpyridine + H2O + O2
-
Lathyrus cicera 2-pyridincarbaldehyde + NH3 + H2O2
-
?
agmatine + H2O + O2
-
Lathyrus cicera ?
-
?
benzylamine + H2O + O2
-
Lathyrus cicera benzaldehyde + NH3 + H2O2
-
?
cadaverine + H2O + O2
-
Lathyrus cicera ?
-
?
histamine + H2O + O2
-
Lathyrus cicera (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
?
putrescine + H2O + O2
-
Lathyrus cicera ?
-
?
spermidine + H2O + O2
-
Lathyrus cicera ?
-
?
spermine + H2O + O2
-
Lathyrus cicera ?
-
?
tyramine + H2O + O2
-
Lathyrus cicera 4-hydroxyphenylethanal + NH3 + H2O2
-
?

Synonyms

Synonyms Comment Organism
LCAO
-
Lathyrus cicera

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.47
-
2-aminomethylpyridine pH 7.2, 25°C Lathyrus cicera
3.7
-
benzylamine pH 7.2, 25°C Lathyrus cicera
10.3
-
histamine pH 7.2, 25°C Lathyrus cicera
28.3
-
spermine pH 7.2, 25°C Lathyrus cicera
32.9
-
tyramine pH 7.2, 25°C Lathyrus cicera
45.9
-
agmatine pH 7.2, 25°C Lathyrus cicera
100
-
spermidine pH 7.2, 25°C Lathyrus cicera
159
-
cadaverine pH 7.2, 25°C Lathyrus cicera
262
-
putrescine pH 7.2, 25°C Lathyrus cicera