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Literature summary for 1.4.3.22 extracted from

  • Schilling, B.; Lerch, K.
    Amine oxidases from Aspergillus niger: identification of a novel flavin-dependent enzyme (1995), Biochim. Biophys. Acta, 1243, 529-537.
    View publication on PubMed
Search for more literature for 1.4.3.22

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.1
-
 tryptamine
-
 Aspergillus niger
0.12
-
 tyramine
-
 Aspergillus niger
0.12
-
 2-Phenylethylamine
-
 Aspergillus niger
0.14
-
 1,4-methylhistamine
-
 Aspergillus niger
0.2
-
 aminohexane
-
 Aspergillus niger
0.24
-
 benzylamine
-
 Aspergillus niger
0.29
-
 serotonin
-
 Aspergillus niger
0.35
-
 aminopentane
-
 Aspergillus niger
0.36
-
 octopamine
-
 Aspergillus niger
0.6
-
 dopamine
-
 Aspergillus niger
0.6
-
 histamine
-
 Aspergillus niger
0.6
-
 aminobutane
-
 Aspergillus niger
1.05
-
 norepinephrine
-
 Aspergillus niger
1.6
-
 Aminopropane
-
 Aspergillus niger

Organism

Organism UniProt Comment Textmining
Aspergillus niger Q12556
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Aspergillus niger

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
45400
-
-
 Aspergillus niger

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,4-methylhistamine + H2O + O2
-
 Aspergillus niger ?
-
 ?
2-(3,4-dihydroxyphenyl)-ethylamine + H2O + O2
-
 Aspergillus niger 3,4-dihydroxyphenylacetaldehyde + NH3 + H2O2
-
 ?
2-phenylethylamine + H2O + O2
-
 Aspergillus niger 2-phenylethanal + NH3 + H2O2
-
 ?
aminobutane + H2O + O2
-
 Aspergillus niger butanal + NH3 + H2O2
-
 ?
aminohexane + H2O + O2
-
 Aspergillus niger hexanal + NH3 + H2O2
-
 ?
aminopentane + H2O + O2
-
 Aspergillus niger pentanal + NH3 + H2O2
-
 ?
aminopropane + H2O + O2
-
 Aspergillus niger propanal + NH3 + H2O2
-
 ?
benzylamine + H2O + O2
-
 Aspergillus niger benzaldehyde + NH3 + H2O2
-
 ?
histamine + H2O + O2
-
 Aspergillus niger (imidazol-4-yl)acetaldehyde + NH3 + H2O2
-
 ?
norepinephrine + H2O + O2
-
 Aspergillus niger ?
-
 ?
octopamine + H2O + O2
-
 Aspergillus niger ?
-
 ?
RCH2NH2 + H2O + O2
-
 Aspergillus niger RCHO + NH3 + H2O2
-
 ?
serotonin + H2O + O2
-
 Aspergillus niger ?
-
 ?
tryptamine
-
 Aspergillus niger ?
-
 ?
tyramine + H2O + O2
-
 Aspergillus niger 4-hydroxyphenylethanal + NH3 + H2O2
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
37
-
 benzylamine
-
 Aspergillus niger
65
-
 norepinephrine
-
 Aspergillus niger
68
-
 1,4-methylhistamine
-
 Aspergillus niger
80
-
 tyramine
-
 Aspergillus niger
95
-
 histamine
-
 Aspergillus niger
100
-
 tryptamine
-
 Aspergillus niger
122
-
 octopamine
-
 Aspergillus niger
132
-
 Aminopropane
-
 Aspergillus niger
132
-
 aminobutane
-
 Aspergillus niger
135
-
 dopamine
-
 Aspergillus niger
136
-
 serotonin
-
 Aspergillus niger
137
-
 2-Phenylethylamine
-
 Aspergillus niger
142
-
 aminopentane
-
 Aspergillus niger
159
-
 aminohexane
-
 Aspergillus niger

Cofactor

Cofactor Comment Organism Structure
2,4,5-trihydroxyphenylalanine quinone
-
 Aspergillus niger