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Literature summary for 1.4.3.22 extracted from

  • Medda, R.; Padiglia, A.; Pedersen, J.Z.; Rotilio, G.; Agro, A.F.; Floris, G.
    The reaction mechanism of copper amine oxidase: detection of intermediates by the use of substrates and inhibitors (1995), Biochemistry, 34, 16375-16381.
    View publication on PubMed
Search for more literature for 1.4.3.22

Inhibitors

Inhibitors Comment Organism Structure
2-methylbenzothiazoline hydrazone competitive inhibition Lens culinaris

Metals/Ions

Metals/Ions Comment Organism Structure
copper removed from enzyme by treatment with diethyldithiocarbamate Lens culinaris

Organism

Organism UniProt Comment Textmining
Lens culinaris
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
100
-
 approx. value Lens culinaris

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-dimethylaminomethylbenzylamine + H2O + O2
-
 Lens culinaris 4-dimethylaminomethylbenzaldehyde + NH3 + H2O2
-
 r
RCH2NH2 + H2O + O2
-
 Lens culinaris RCHO + NH3 + H2O2
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.000233
-
 4-dimethylaminomethylbenzylamine
-
 Lens culinaris
155
-
 putrescine
-
 Lens culinaris

Cofactor

Cofactor Comment Organism Structure
2,4,5-trihydroxyphenylalanine quinone
-
 Lens culinaris

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.2
-
 2-methylbenzothiazoline hydrazone
-
 Lens culinaris