Literature summary for 1.4.3.21 extracted from

Carpene, C.; Iffiu-Soltesz, Z.; Bour, S.; Prevot, D.; Valet, P.
Reduction of fat deposition by combined inhibition of monoamine oxidases and semicarbazide-sensitive amine oxidases in obese Zucker rats (2007), Pharmacol. Res., 56, 522-530.

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Inhibitors

Inhibitors	Comment	Organism	Structure
Semicarbazide	irreversible inhibitor. Pargyline + semicarbazide-induced reduction of fat deposition results from decreased food intake and from impaired MAO (EC 1.4.3.4) and SSAO-dependent lipogenic and antilipolytic actions of endogenous or alimentary amines	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
benzylamine + H2O + O2	-	Rattus norvegicus	benzaldehyde + NH3 + H2O2	-	?
tyramine + H2O + O2	-	Rattus norvegicus	4-hydroxyphenylethanal + NH3 + H2O2	-	?

Synonyms

Synonyms	Comment	Organism
SSAO	-	Rattus norvegicus

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Release 2023.1 (January 2023)