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Literature summary for 1.4.3.2 extracted from

  • Ribeiro, P.H.; Zuliani, J.P.; Fernandes, C.F.; Calderon, L.A.; Stabeli, R.G.; Nomizo, A.; Soares, A.M.
    Mechanism of the cytotoxic effect of L-amino acid oxidase isolated from Bothrops alternatus snake venom (2016), Int. J. Biol. Macromol., 92, 329-337 .
    View publication on PubMed

Application

Application Comment Organism
medicine the enzyme has a strong selective cytotoxic activity on tumor cell lines (JURKAT, SK-BR-3 and B16F10) Bothrops alternatus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
123000
-
gel filtration Bothrops alternatus

Organism

Organism UniProt Comment Textmining
Bothrops alternatus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
venom
-
Bothrops alternatus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Leu + H2O + O2
-
Bothrops alternatus 2-oxo-4-methylvaleric acid + NH3 + H2O2
-
?

Subunits

Subunits Comment Organism
homodimer 2 * 66000, SDS-PAGE Bothrops alternatus

Synonyms

Synonyms Comment Organism
LAAO-I
-
Bothrops alternatus

Cofactor

Cofactor Comment Organism Structure
FAD
-
Bothrops alternatus

pI Value

Organism Comment pI Value Maximum pI Value
Bothrops alternatus isoelectric focusing
-
5.3