Application | Comment | Organism |
---|---|---|
drug development | ACTX-6 demonstrates cytotoxicity in vitro and can inhibit tumor growth in vivo. It can markedly increase accumulation of sub-G1 phase, which suggests that this enzyme can induce apoptosis. ACTX-6 is a potential substance to develop into an antitumor drug | Deinagkistrodon acutus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
96000 | - |
gel filtration, mass spectrometry | Deinagkistrodon acutus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Deinagkistrodon acutus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
by gel filtration | Deinagkistrodon acutus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
venom | - |
Deinagkistrodon acutus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-leucine + H2O + O2 | one of the best substrates | Deinagkistrodon acutus | 4-methyl-2-oxopentanoic acid + NH3 + H2O2 | - |
? | |
L-methionine + H2O + O2 | one of the best substrates | Deinagkistrodon acutus | 4-methylsulfanyl-2-oxobutanoate + NH3 + H2O2 | - |
? | |
L-phenylalanine + H2O + O2 | one of the best substrates | Deinagkistrodon acutus | phenylpyruvate + NH3 + H2O2 | - |
? | |
L-tryptophan + H2O + O2 | one of the best substrates | Deinagkistrodon acutus | 3-indole-2-oxopropanoate + NH3 + H2O2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | SDS-PAGE | Deinagkistrodon acutus |
Synonyms | Comment | Organism |
---|---|---|
ACTX-6 | - |
Deinagkistrodon acutus |
LAAO | - |
Deinagkistrodon acutus |