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Literature summary for 1.4.3.2 extracted from

  • Tong, H.; Chen, W.; Shi, W.; Qi, F.; Dong, X.
    SO-LAAO, a novel L-amino acid oxidase that enables Streptococcus oligofermentans to outcompete Streptococcus mutans by generating H2O2 from peptone (2008), J. Bacteriol., 190, 4716-4721.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information peptone up-regulates expression of the aaoSo gene Streptococcus cristatus

Application

Application Comment Organism
additional information LAAO contributes to competitive edge of Streptococcus oligofermentans over Streptococcus mutans in mixed-species biofilm with peptone Streptococcus cristatus

Cloned(Commentary)

Cloned (Comment) Organism
overexpressed in Escherichia coli BL21(DE3)pLysS Streptococcus cristatus

Protein Variants

Protein Variants Comment Organism
additional information an aaoSo mutant loses H2O2 formation from L-amino acids. Inhibition by Streptococcus oligofermentans of Streptococcus mutans in a peptone-rich mixed-species biofilm is greatly reduced Streptococcus cristatus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
43000
-
x * 43000, SDS-PAGE Streptococcus cristatus

Organism

Organism UniProt Comment Textmining
Streptococcus cristatus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
by immobilized metal ion affinity chromatography Streptococcus cristatus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine + H2O + O2
-
Streptococcus cristatus 2-oxo-5-guanidinovaleric acid + NH3 + H2O2
-
?
L-asparagine + H2O + O2
-
Streptococcus cristatus alpha-ketosuccinamic acid + NH3 + H2O2
-
?
L-aspartic acid + H2O + O2
-
Streptococcus cristatus oxaloacetate + NH3 + H2O2
-
?
L-glutamine + H2O + O2
-
Streptococcus cristatus 5-amino-2,5-dioxopentanoate + NH3 + H2O2
-
?
L-isoleucine + H2O + O2
-
Streptococcus cristatus alpha-keto-beta-methyl-pentanoic acid + NH3 + H2O2
-
?
L-lysine + H2O + O2
-
Streptococcus cristatus 6-amino-2-oxohexanoic acid + NH3 + H2O2
-
?
L-tryptophan + H2O + O2
-
Streptococcus cristatus 3-indole-2-oxopropanoate + NH3 + H2O2
-
?
additional information does not catalyze N-acetyL-L-cysteine and cis-4-hydroxyl-L-proline oxidation Streptococcus cristatus ?
-
?

Subunits

Subunits Comment Organism
? x * 43000, SDS-PAGE Streptococcus cristatus

Synonyms

Synonyms Comment Organism
LAAO
-
Streptococcus cristatus