Literature summary for 1.4.3.2 extracted from

Ande, S.R.; Kommoju, P.R.; Draxl, S.; Murkovic, M.; Macheroux, P.; Ghisla, S.; Ferrando-May, E.
Mechanisms of cell death induction by L-amino acid oxidase, a major component of ophidian venom (2006), Apoptosis, 11, 1439-1451.

Search for more literature for 1.4.3.2

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Calloselasma rhodostoma	enzyme induces necrosis and apoptosis in Jurkat cells, in presence of catalase that scavenges H2O2 a switch to apoptosis is observed	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Calloselasma rhodostoma	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
glycoprotein	desialysation reduces cytotoxicity of enzyme. Glycan moiety of enzyme is involved in binding and internalization to Jurkat cells	Calloselasma rhodostoma

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enzyme induces necrosis and apoptosis in Jurkat cells, in presence of catalase that scavenges H2O2 a switch to apoptosis is observed	Calloselasma rhodostoma	?	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)