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Literature summary for 1.4.3.14 extracted from

  • Pokrovsky, V.S.; Lukashev, A.N.; Babayeva, G.; Karshieva, S.S.; Arinbasarova, A.Y.; Medentzev, A.G.; Komarova, M.V.; Lukasheva, E.V.
    Plasma pharmacokinetics and tissue distribution of L-lysine alpha-oxidase from Trichoderma cf. aureoviride RIFAI VKM F- 4268D in mice (2021), Amino Acids, 53, 111-118 .
    View publication on PubMed

Application

Application Comment Organism
pharmacology promising enzyme for further investigation as a potential anticancer agent. Antitumor effect against murine tumors and human cancer xenografts Trichoderma aureoviride

Organism

Organism UniProt Comment Textmining
Trichoderma aureoviride
-
-
-
Trichoderma aureoviride Rifai VKM F-4268D
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Trichoderma aureoviride

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-lysine + O2 + H2O
-
Trichoderma aureoviride 6-amino-2-oxohexanoate + NH3 + H2O2
-
?
L-lysine + O2 + H2O
-
Trichoderma aureoviride Rifai VKM F-4268D 6-amino-2-oxohexanoate + NH3 + H2O2
-
?

Subunits

Subunits Comment Organism
dimer 2 * 60000 Trichoderma aureoviride

Cofactor

Cofactor Comment Organism Structure
FAD FAD-dependent enzyme Trichoderma aureoviride