Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
extracellular space | - |
Homo sapiens | 5615 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | lysyl oxidase protein expression is very scarce in normal hearts, it is highly expressed in failing hearts | Homo sapiens | - |
myocardium | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
LOX | - |
Homo sapiens |
lysyl oxidase | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | ability of torasemide to correct both lysyl oxidase overexpression and enhanced collagen cross-linking | down |
General Information | Comment | Organism |
---|---|---|
malfunction | the enzyme regulates collagen cross-linking, which is increased in heart failure patients compared with healthy hearts. Enzyme overexpression is associated with enhanced collagen cross-linking in the failing human heart. Ability of torasemide to correct both lysyl oxidase overexpression and enhanced collagen cross-linking | Homo sapiens |
physiological function | the enzyme regulates collagen cross-linking | Homo sapiens |