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Literature summary for 1.4.3.13 extracted from

  • Sakai, M.; Kato, H.; Sano, A.; Tanaka, N.; Inose, T.; Kimura, H.; Sohda, M.; Nakajima, M.; Kuwano, H.
    Expression of lysyl oxidase is correlated with lymph node metastasis and poor prognosis in esophageal squamous cell carcinoma (2009), Ann. Surg. Oncol., 16, 2494-2501.
    View publication on PubMed

Application

Application Comment Organism
diagnostics LOX can serve as a predictive marker of lymph node metastasis and prognosis in esophageal squamous cell carcinoma. Overall survival rates of the patients with esophageal squamous cell carcinoma with high LOX expression are significantly lower than those of the patients with esophageal squamous cell carcinoma with low LOX expression Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
RT-PCR enzyme expression analysis in esophageal squamous cell carcinoma cells, overview Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
extracellular
-
Homo sapiens
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens LOX is an extracellular matrix-remodeling enzyme involved in regulation of tumor metastasis ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
esophageal squamous cell carcinoma cell
-
Homo sapiens
-
TE-1 cell
-
Homo sapiens
-
TE-13 cell
-
Homo sapiens
-
TE-15 cell
-
Homo sapiens
-
TE-2 cell
-
Homo sapiens
-
TE-8 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information LOX is an extracellular matrix-remodeling enzyme involved in regulation of tumor metastasis Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
LOX
-
Homo sapiens
lysyl oxidase
-
Homo sapiens

General Information

General Information Comment Organism
physiological function overall survival rates of the patients with esophageal squamous cell carcinoma with high LOX expression are significantly lower than those of the patients with esophageal squamous cell carcinoma with low LOX expression Homo sapiens