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Literature summary for 1.4.3.13 extracted from

  • Laczko, R.; Szauter, K.M.; Jansen, M.K.; Hollosi, P.; Muranyi, M.; Molnar, J.; Fong, K.S.; Hinek, A.; Csiszar, K.
    Active lysyl oxidase (LOX) correlates with focal adhesion kinase (FAK)/paxillin activation and migration in invasive astrocytes (2007), Neuropathol. Appl. Neurobiol., 33, 631-643.
    View publication on PubMed
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Activating Compound

Activating Compound Comment Organism Structure
additional information active LOX promotes focal adhesion kinase activation and invasive/migratory behaviour of astrocytes Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
beta-aminopropionitrile 0.5 mM Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
30000
-
 mature enzyme, SDS-PAGE Homo sapiens
50000
-
 glycosylated immature protein, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
astrocyte
-
 Homo sapiens
-
astrocytoma cell
-
 Homo sapiens
-
brain
-
 Homo sapiens
-
glioblastoma cell
-
 Homo sapiens
-
U-251 cell
-
 Homo sapiens
-
U343-MG-A cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,5-diaminopentane + O2 + H2O
-
 Homo sapiens ? + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
LOX
-
 Homo sapiens
lysyl oxidase
-
 Homo sapiens