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Literature summary for 1.4.3.13 extracted from

  • Lelievre, E.; Hinek, A.; Lupu, F.; Buquet, C.; Soncin, F.; Mattot, V.
    VE-statin/egfl7 regulates vascular elastogenesis by interacting with lysyl oxidases (2008), EMBO J., 27, 1658-1670.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in MEF cells Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
VE-statin/egfl7 protein interacts with the catalytic domain of lysyl oxidase thereby preventing the crosslink of tropoelastin molecules into mature elastin polymers and regulating vascular elastogenesis Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
peptidyl-L-lysyl-peptide + O2 + H2O
-
Mus musculus peptidyl-allysyl-peptide + NH3 + H2O2
-
?

Synonyms

Synonyms Comment Organism
LOX
-
Mus musculus
lysyl oxidase
-
Mus musculus