Literature summary for 1.4.1.3 extracted from

Shoemaker, M.T.; Haley, B.E.
Identification of a guanine binding domain peptide of the GTP binding site of glutamate dehydrogenase: Isolation with metal-chelate affinity chromatography (1993), Biochemistry, 32, 1883-1890.

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Activating Compound

Activating Compound	Comment	Organism	Structure
8-azidoguanosine 5'-diphosphate	used for affinity photolabeling	Bos taurus

Inhibitors

Inhibitors	Comment	Organism	Structure
8-azidoguanosine 5'-triphosphate	used for affinity photolabeling, 0.1 mM, 95% inhibition	Bos taurus
GTP	0.06 mM, 95% inhibition	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-glutamate + H2O + NAD(P)+	-	Bos taurus	2-oxoglutarate + NH3 + NAD(P)H	-	r

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0006	-	GTP	-	Bos taurus
0.005	-	8-azidoguanosine 5'-triphosphate	-	Bos taurus

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Release 2023.1 (January 2023)