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Literature summary for extracted from

  • Langridge, W.H.R.; Komuniecki, P.; DeToma, F.J.
    Isolation and regulatory properties of two glutamate dehydrogenases from the cellular slime mold Dictyostelium discoideum (1977), Arch. Biochem. Biophys., 178, 581-587.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
ADP stimulation Dictyostelium discoideum
AMP 1 mM, reaction velocity increases 15fold at saturating NAD+ and glutamate levels Dictyostelium discoideum


Inhibitors Comment Organism Structure
ATP strong inhibition Dictyostelium discoideum


Localization Comment Organism GeneOntology No. Textmining
Dictyostelium discoideum 5739


Organism UniProt Comment Textmining
Dictyostelium discoideum

Purification (Commentary)

Purification (Comment) Organism
Dictyostelium discoideum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate + H2O + NAD(P)+
Dictyostelium discoideum 2-oxoglutarate + NH3 + NAD(P)H


Cofactor Comment Organism Structure
NAD+ 2 times higher reaction rate than with NADP+ Dictyostelium discoideum