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Literature summary for 1.4.1.2 extracted from

  • Beaufay, F.; Coppine, J.; Mayard, A.; Laloux, G.; De Bolle, X.; Hallez, R.
    A NAD-dependent glutamate dehydrogenase coordinates metabolism with cell division in Caulobacter crescentus (2015), EMBO J., 34, 1786-1800 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Caulobacter vibrioides A0A0H3C571
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Synonyms

Synonyms Comment Organism
CCNA_00086
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Caulobacter vibrioides
GdhZ
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Caulobacter vibrioides

General Information

General Information Comment Organism
physiological function enzyme coordinates metabolism with cell division. Enzymatically active NAD-dependent glutamate dehydrogenase GdhZ directly interferes with FtsZ polymerization by stimulating its GTPase activity, and oxidoreductase-like KidO bound to NADH destabilizes lateral interactions between FtsZ protofilaments. Both GdhZ and KidO share the same regulatory network to concomitantly stimulate the rapid disassembly of the Z-ring, necessary for the subsequent release of progeny cells Caulobacter vibrioides