BRENDA - Enzyme Database show
show all sequences of 1.4.1.16

Characterization of meso-diaminopimelate dehydrogenase from Corynebacterium glutamicum and its distribution in bacteria

Misono, H.; Ogasawara, M.; Nagasaki, S.; Agric. Biol. Chem. 50, 2729-2734 (1986)
No PubMed abstract available

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
Cu2+
-
Brevibacterium sp.
Cu2+
0.01 mM, 82% inhibition
Corynebacterium glutamicum
D-2,6-diaminopimelate
10 mM, 49% inhibition
Corynebacterium glutamicum
D-2,6-diaminopimelate
-
Lysinibacillus sphaericus
HgCl2
-
Brevibacterium sp.
HgCl2
0.01 mM, 92% inhibition
Corynebacterium glutamicum
HgCl2
-
Lysinibacillus sphaericus
iodoacetate
-
Brevibacterium sp.
iodoacetate
1 mM, 77% inhibition
Corynebacterium glutamicum
iodoacetate
-
Lysinibacillus sphaericus
L-2,6-diaminopimelate
10 mM, 27% inhibition
Corynebacterium glutamicum
L-2,6-diaminopimelate
-
Lysinibacillus sphaericus
L-cysteine
5 mM, 99% inhibition
Corynebacterium glutamicum
Li+
1 mM, 32% inhibition
Corynebacterium glutamicum
N-ethylmaleimide
-
Brevibacterium sp.
N-ethylmaleimide
1 mM, 39% inhibition
Corynebacterium glutamicum
N-ethylmaleimide
-
Lysinibacillus sphaericus
Ni2+
-
Brevibacterium sp.
Ni2+
1 mM, 36% inhibition
Corynebacterium glutamicum
p-chloromercuribenzoate
-
Corynebacterium glutamicum
p-chloromercuribenzoate
-
Lysinibacillus sphaericus
thioglycolate
5 mM, 62% inhibition
Corynebacterium glutamicum
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.083
0.14
NADP+
-
Corynebacterium glutamicum
0.083
0.14
NADP+
-
Brevibacterium sp.
0.083
0.14
NADP+
-
Lysinibacillus sphaericus
0.13
-
NADPH
-
Corynebacterium glutamicum
0.28
-
L-2-amino-6-oxopimelate
-
Corynebacterium glutamicum
2
10
NAD+
-
Brevibacterium sp.
2
10
NAD+
-
Corynebacterium glutamicum
10
-
NAD+
-
Corynebacterium glutamicum
36
-
NH3
-
Corynebacterium glutamicum
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
39000
-
2 * 39000, SDS-PAGE
Corynebacterium glutamicum
70000
-
-
Brevibacterium sp.
70000
-
gel filtration
Corynebacterium glutamicum
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Lysinibacillus sphaericus
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Lysinibacillus sphaericus
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Corynebacterium glutamicum
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Corynebacterium glutamicum
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Pseudomonas fragi
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Pseudomonas fragi
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Brevibacterium sp.
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Brevibacterium sp.
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Morganella morganii
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Morganella morganii
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Providencia rettgeri
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Providencia rettgeri
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Pseudomonas cruciviae
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Pseudomonas cruciviae
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Glutamicibacter protophormiae
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Glutamicibacter protophormiae
r
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Achromobacter polymorph
-
very low activity
-
Achromobacter superficialis
-
very low activity
-
Agrobacterium tumefaciens
-
very low activity
-
Alcaligenes viscolactis
-
low activity
-
Bacillus amyloliquefaciens
-
very low activity
-
Bacillus cereus
-
very low activity
-
Bacillus licheniformis
-
very low activity
-
Bacterium mycoides
-
very low activity
-
Brevibacillus brevis
-
low activity
-
Brevibacterium sp.
-
-
-
Corynebacterium ammoniagenes
-
low activity
-
Corynebacterium glutamicum
-
strain ATCC 13032
-
Corynebacterium pseudodiphtheriticum
-
low activity
-
Enterobacter cloacae
-
low activity
-
Flavobacterium suaveolens
-
low activity
-
Glutamicibacter protophormiae
-
-
-
Hafnia alvei
-
very low activity
-
Kocuria rosea
-
very low activity
-
Lysinibacillus sphaericus
-
-
-
Micrococcus luteus
-
low activity
-
Morganella morganii
-
-
-
no activity in Escherichia coli
-
strains ICR 0010, K12, ICR 0050 and IFO 3301
-
no activity in Klebsiella pneumoniae
-
strains IFO 125059 and 12019
-
no activity in Staphylococcus aureus
-
-
-
Providencia rettgeri
-
-
-
Pseudomonas aeruginosa
-
very low activity
-
Pseudomonas alkanolytica
-
very low activity
-
Pseudomonas chlororaphis subsp. aureofaciens
-
very low activity
-
Pseudomonas cruciviae
-
-
-
Pseudomonas fragi
-
-
-
Pseudomonas putida
-
very low activity
-
Terrabacter tumescens
-
very low activity
-
Purification (Commentary)
Commentary
Organism
-
Corynebacterium glutamicum
Specific Activity [micromol/min/mg]
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
131.6
-
-
Corynebacterium glutamicum
Storage Stability
Storage Stability
Organism
-20C, 0.01 M potassium phosphate buffer, pH 7.4, 0.01% 2-mercaptoethanol, 10% glycerol, 1 year
Lysinibacillus sphaericus
-20C, 0.01 M potassium phosphate buffer, pH 7.4, 0.01% 2-mercaptoethanol, 10% glycerol, 1 year
Corynebacterium glutamicum
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Brevibacillus brevis
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Brevibacillus brevis
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Enterobacter cloacae
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Enterobacter cloacae
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Lysinibacillus sphaericus
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Lysinibacillus sphaericus
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Kocuria rosea
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Kocuria rosea
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas aeruginosa
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas aeruginosa
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas putida
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas putida
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Bacillus cereus
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Bacillus cereus
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Corynebacterium glutamicum
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Corynebacterium glutamicum
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Micrococcus luteus
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Micrococcus luteus
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Bacillus licheniformis
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Bacillus licheniformis
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Bacillus amyloliquefaciens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Bacillus amyloliquefaciens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas fragi
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas fragi
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Agrobacterium tumefaciens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Agrobacterium tumefaciens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Brevibacterium sp.
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Brevibacterium sp.
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Morganella morganii
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Morganella morganii
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Hafnia alvei
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Hafnia alvei
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Corynebacterium ammoniagenes
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Corynebacterium ammoniagenes
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Providencia rettgeri
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Providencia rettgeri
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas cruciviae
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas cruciviae
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas chlororaphis subsp. aureofaciens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas chlororaphis subsp. aureofaciens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Glutamicibacter protophormiae
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Glutamicibacter protophormiae
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Corynebacterium pseudodiphtheriticum
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Corynebacterium pseudodiphtheriticum
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Alcaligenes viscolactis
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Alcaligenes viscolactis
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Achromobacter polymorph
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Achromobacter polymorph
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas alkanolytica
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas alkanolytica
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Flavobacterium suaveolens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Flavobacterium suaveolens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Terrabacter tumescens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Terrabacter tumescens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Bacterium mycoides
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Bacterium mycoides
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Achromobacter superficialis
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Achromobacter superficialis
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Lysinibacillus sphaericus
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Lysinibacillus sphaericus
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Corynebacterium glutamicum
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Corynebacterium glutamicum
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Pseudomonas fragi
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Pseudomonas fragi
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Brevibacterium sp.
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Brevibacterium sp.
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Morganella morganii
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Morganella morganii
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Providencia rettgeri
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Providencia rettgeri
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Pseudomonas cruciviae
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Pseudomonas cruciviae
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Glutamicibacter protophormiae
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Glutamicibacter protophormiae
r
Subunits
Subunits
Commentary
Organism
dimer
-
Brevibacterium sp.
dimer
2 * 39000, SDS-PAGE
Corynebacterium glutamicum
dimer
-
Lysinibacillus sphaericus
Temperature Stability [C]
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
45
-
unstable above
Corynebacterium glutamicum
45
-
unstable above
Lysinibacillus sphaericus
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.9
-
reductive amination of 2-amino-6-oxopimelate
Corynebacterium glutamicum
9
-
oxidative deamination of meso-2,6-diaminopimelate
Corynebacterium glutamicum
pH Stability
pH Stability
pH Stability Maximum
Commentary
Organism
6.5
7
-
Corynebacterium glutamicum
Cofactor
Cofactor
Commentary
Organism
Structure
NADH
3% activity of that with NADP+
Corynebacterium glutamicum
NADH
3% activity of that with NADP+
Brevibacterium sp.
NADPH
-
Achromobacter polymorph
NADPH
-
Achromobacter superficialis
NADPH
-
Agrobacterium tumefaciens
NADPH
-
Alcaligenes viscolactis
NADPH
-
Bacillus amyloliquefaciens
NADPH
-
Bacillus cereus
NADPH
-
Bacillus licheniformis
NADPH
-
Bacterium mycoides
NADPH
-
Brevibacillus brevis
NADPH
-
Corynebacterium ammoniagenes
NADPH
-
Corynebacterium pseudodiphtheriticum
NADPH
-
Enterobacter cloacae
NADPH
-
Flavobacterium suaveolens
NADPH
-
Glutamicibacter protophormiae
NADPH
-
Hafnia alvei
NADPH
-
Kocuria rosea
NADPH
-
Micrococcus luteus
NADPH
-
Morganella morganii
NADPH
-
Providencia rettgeri
NADPH
-
Pseudomonas aeruginosa
NADPH
-
Pseudomonas alkanolytica
NADPH
-
Pseudomonas chlororaphis subsp. aureofaciens
NADPH
-
Pseudomonas cruciviae
NADPH
-
Pseudomonas fragi
NADPH
-
Pseudomonas putida
NADPH
-
Terrabacter tumescens
NADPH
-
Brevibacterium sp.
NADPH
-
Lysinibacillus sphaericus
NADPH
-
Corynebacterium glutamicum
Ki Value [mM]
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2
-
D-2,6-diaminopimelate
-
Corynebacterium glutamicum
8.5
-
L-2,6-diaminopimelate
-
Corynebacterium glutamicum
Cofactor (protein specific)
Cofactor
Commentary
Organism
Structure
NADH
3% activity of that with NADP+
Corynebacterium glutamicum
NADH
3% activity of that with NADP+
Brevibacterium sp.
NADPH
-
Achromobacter polymorph
NADPH
-
Achromobacter superficialis
NADPH
-
Agrobacterium tumefaciens
NADPH
-
Alcaligenes viscolactis
NADPH
-
Bacillus amyloliquefaciens
NADPH
-
Bacillus cereus
NADPH
-
Bacillus licheniformis
NADPH
-
Bacterium mycoides
NADPH
-
Brevibacillus brevis
NADPH
-
Corynebacterium ammoniagenes
NADPH
-
Corynebacterium pseudodiphtheriticum
NADPH
-
Enterobacter cloacae
NADPH
-
Flavobacterium suaveolens
NADPH
-
Glutamicibacter protophormiae
NADPH
-
Hafnia alvei
NADPH
-
Kocuria rosea
NADPH
-
Micrococcus luteus
NADPH
-
Morganella morganii
NADPH
-
Providencia rettgeri
NADPH
-
Pseudomonas aeruginosa
NADPH
-
Pseudomonas alkanolytica
NADPH
-
Pseudomonas chlororaphis subsp. aureofaciens
NADPH
-
Pseudomonas cruciviae
NADPH
-
Pseudomonas fragi
NADPH
-
Pseudomonas putida
NADPH
-
Terrabacter tumescens
NADPH
-
Brevibacterium sp.
NADPH
-
Lysinibacillus sphaericus
NADPH
-
Corynebacterium glutamicum
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
Cu2+
-
Brevibacterium sp.
Cu2+
0.01 mM, 82% inhibition
Corynebacterium glutamicum
D-2,6-diaminopimelate
10 mM, 49% inhibition
Corynebacterium glutamicum
D-2,6-diaminopimelate
-
Lysinibacillus sphaericus
HgCl2
-
Brevibacterium sp.
HgCl2
0.01 mM, 92% inhibition
Corynebacterium glutamicum
HgCl2
-
Lysinibacillus sphaericus
iodoacetate
-
Brevibacterium sp.
iodoacetate
1 mM, 77% inhibition
Corynebacterium glutamicum
iodoacetate
-
Lysinibacillus sphaericus
L-2,6-diaminopimelate
10 mM, 27% inhibition
Corynebacterium glutamicum
L-2,6-diaminopimelate
-
Lysinibacillus sphaericus
L-cysteine
5 mM, 99% inhibition
Corynebacterium glutamicum
Li+
1 mM, 32% inhibition
Corynebacterium glutamicum
N-ethylmaleimide
-
Brevibacterium sp.
N-ethylmaleimide
1 mM, 39% inhibition
Corynebacterium glutamicum
N-ethylmaleimide
-
Lysinibacillus sphaericus
Ni2+
-
Brevibacterium sp.
Ni2+
1 mM, 36% inhibition
Corynebacterium glutamicum
p-chloromercuribenzoate
-
Corynebacterium glutamicum
p-chloromercuribenzoate
-
Lysinibacillus sphaericus
thioglycolate
5 mM, 62% inhibition
Corynebacterium glutamicum
Ki Value [mM] (protein specific)
Ki Value [mM]
Ki Value maximum [mM]
Inhibitor
Commentary
Organism
Structure
2
-
D-2,6-diaminopimelate
-
Corynebacterium glutamicum
8.5
-
L-2,6-diaminopimelate
-
Corynebacterium glutamicum
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.083
0.14
NADP+
-
Corynebacterium glutamicum
0.083
0.14
NADP+
-
Brevibacterium sp.
0.083
0.14
NADP+
-
Lysinibacillus sphaericus
0.13
-
NADPH
-
Corynebacterium glutamicum
0.28
-
L-2-amino-6-oxopimelate
-
Corynebacterium glutamicum
2
10
NAD+
-
Brevibacterium sp.
2
10
NAD+
-
Corynebacterium glutamicum
10
-
NAD+
-
Corynebacterium glutamicum
36
-
NH3
-
Corynebacterium glutamicum
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
39000
-
2 * 39000, SDS-PAGE
Corynebacterium glutamicum
70000
-
-
Brevibacterium sp.
70000
-
gel filtration
Corynebacterium glutamicum
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Lysinibacillus sphaericus
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Lysinibacillus sphaericus
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Corynebacterium glutamicum
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Corynebacterium glutamicum
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Pseudomonas fragi
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Pseudomonas fragi
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Brevibacterium sp.
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Brevibacterium sp.
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Morganella morganii
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Morganella morganii
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Providencia rettgeri
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Providencia rettgeri
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Pseudomonas cruciviae
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Pseudomonas cruciviae
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
Glutamicibacter protophormiae
-
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
Glutamicibacter protophormiae
r
Purification (Commentary) (protein specific)
Commentary
Organism
-
Corynebacterium glutamicum
Specific Activity [micromol/min/mg] (protein specific)
Specific Activity Minimum [mol/min/mg]
Specific Activity Maximum [mol/min/mg]
Commentary
Organism
131.6
-
-
Corynebacterium glutamicum
Storage Stability (protein specific)
Storage Stability
Organism
-20C, 0.01 M potassium phosphate buffer, pH 7.4, 0.01% 2-mercaptoethanol, 10% glycerol, 1 year
Lysinibacillus sphaericus
-20C, 0.01 M potassium phosphate buffer, pH 7.4, 0.01% 2-mercaptoethanol, 10% glycerol, 1 year
Corynebacterium glutamicum
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Brevibacillus brevis
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Brevibacillus brevis
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Enterobacter cloacae
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Enterobacter cloacae
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Lysinibacillus sphaericus
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Lysinibacillus sphaericus
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Kocuria rosea
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Kocuria rosea
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas aeruginosa
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas aeruginosa
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas putida
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas putida
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Bacillus cereus
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Bacillus cereus
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Corynebacterium glutamicum
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Corynebacterium glutamicum
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Micrococcus luteus
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Micrococcus luteus
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Bacillus licheniformis
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Bacillus licheniformis
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Bacillus amyloliquefaciens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Bacillus amyloliquefaciens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas fragi
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas fragi
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Agrobacterium tumefaciens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Agrobacterium tumefaciens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Brevibacterium sp.
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Brevibacterium sp.
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Morganella morganii
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Morganella morganii
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Hafnia alvei
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Hafnia alvei
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Corynebacterium ammoniagenes
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Corynebacterium ammoniagenes
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Providencia rettgeri
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Providencia rettgeri
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas cruciviae
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas cruciviae
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas chlororaphis subsp. aureofaciens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas chlororaphis subsp. aureofaciens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Glutamicibacter protophormiae
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Glutamicibacter protophormiae
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Corynebacterium pseudodiphtheriticum
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Corynebacterium pseudodiphtheriticum
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Alcaligenes viscolactis
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Alcaligenes viscolactis
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Achromobacter polymorph
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Achromobacter polymorph
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Pseudomonas alkanolytica
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Pseudomonas alkanolytica
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Flavobacterium suaveolens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Flavobacterium suaveolens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Terrabacter tumescens
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Terrabacter tumescens
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Bacterium mycoides
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Bacterium mycoides
r
L-2-amino-6-oxoheptanedioate + NH3 + NAD(P)H
-
391505
Achromobacter superficialis
meso-2,6-diaminoheptanedioate + H2O + NAD(P)+
-
391505
Achromobacter superficialis
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Lysinibacillus sphaericus
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Lysinibacillus sphaericus
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Corynebacterium glutamicum
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Corynebacterium glutamicum
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Pseudomonas fragi
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Pseudomonas fragi
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Brevibacterium sp.
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Brevibacterium sp.
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Morganella morganii
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Morganella morganii
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Providencia rettgeri
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Providencia rettgeri
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Pseudomonas cruciviae
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Pseudomonas cruciviae
r
L-2-amino-6-oxoheptanedioate + NH3 + NADPH
-
391505
Glutamicibacter protophormiae
meso-2,6-diaminoheptanedioate + H2O + NADP+
-
391505
Glutamicibacter protophormiae
r
Subunits (protein specific)
Subunits
Commentary
Organism
dimer
-
Brevibacterium sp.
dimer
2 * 39000, SDS-PAGE
Corynebacterium glutamicum
dimer
-
Lysinibacillus sphaericus
Temperature Stability [C] (protein specific)
Temperature Stability Minimum [C]
Temperature Stability Maximum [C]
Commentary
Organism
45
-
unstable above
Corynebacterium glutamicum
45
-
unstable above
Lysinibacillus sphaericus
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
7.9
-
reductive amination of 2-amino-6-oxopimelate
Corynebacterium glutamicum
9
-
oxidative deamination of meso-2,6-diaminopimelate
Corynebacterium glutamicum
pH Stability (protein specific)
pH Stability
pH Stability Maximum
Commentary
Organism
6.5
7
-
Corynebacterium glutamicum
Other publictions for EC 1.4.1.16
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [C]
Temperature Range [C]
Temperature Stability [C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [C] (protein specific)
Temperature Range [C] (protein specific)
Temperature Stability [C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
741705
Gao
A newly determined member of ...
Symbiobacterium thermophilum, Symbiobacterium thermophilum IAM14863
Appl. Environ. Microbiol.
83
e00476
2017
-
-
1
-
2
-
-
12
-
-
-
2
-
3
-
-
-
-
-
-
-
-
11
-
-
-
-
12
-
-
-
1
-
-
-
-
-
1
1
-
2
-
-
-
-
12
-
-
-
2
-
-
-
-
-
-
-
-
11
-
-
-
-
12
-
-
-
-
-
-
-
-
12
12
741514
Akita
Structural insight into the t ...
Ureibacillus thermosphaericus
Acta Crystallogr. Sect. D
71
1136-1146
2015
-
-
1
1
-
-
-
-
-
-
-
1
-
4
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742282
Liu
Structural analysis reveals t ...
Clostridium tetani, Clostridium tetani E88
ChemBioChem
16
924-929
2015
-
-
1
1
1
-
-
-
-
-
-
2
-
3
-
-
1
-
-
-
3
-
8
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
1
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
3
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742303
Zhao
Effect of residue Y76 on co-e ...
Symbiobacterium thermophilum
Chin. J. Biotechnol.
31
1108-1118
2015
-
-
-
-
1
-
-
-
-
-
-
1
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
743593
Stone
Identification of small-molec ...
Porphyromonas gingivalis, Porphyromonas gingivalis W83
PLoS ONE
10
e0141126
2015
-
-
1
-
-
-
11
2
-
-
-
2
-
5
-
-
1
-
-
-
-
-
2
1
-
-
-
-
-
-
-
1
-
-
4
-
-
1
1
-
-
-
4
11
-
2
-
-
-
2
-
-
-
1
-
-
-
-
2
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
742276
Liu
Structural and mutational stu ...
Symbiobacterium thermophilum
ChemBioChem
15
217-222
2014
-
-
1
1
9
-
-
-
-
-
-
1
-
2
-
-
1
-
-
-
-
-
3
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
9
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
724034
Gao
Engineering the meso-diaminopi ...
Symbiobacterium thermophilum
Appl. Environ. Microbiol.
79
5078-5081
2013
-
-
1
-
10
-
-
9
-
-
-
1
-
2
-
-
1
-
-
-
10
-
2
-
1
-
-
10
1
-
-
2
-
-
-
-
-
1
2
-
10
-
-
-
-
9
-
-
-
1
-
-
-
1
-
-
10
-
2
-
1
-
-
10
1
-
-
-
-
1
1
-
-
-
724026
Gao
A novel meso-Diaminopimelate d ...
Symbiobacterium thermophilum
Appl. Environ. Microbiol.
78
8595-8600
2012
-
1
1
-
3
-
-
8
-
-
-
2
-
3
-
-
1
-
-
-
-
-
4
-
1
-
4
8
2
-
-
2
-
-
-
-
1
1
2
-
3
-
-
-
-
8
-
-
-
2
-
-
-
1
-
-
-
-
4
-
1
-
4
8
2
-
-
-
-
1
1
-
-
-
724643
Akita
Creation of a thermostable NAD ...
Ureibacillus thermosphaericus, Ureibacillus thermosphaericus A1
Biotechnol. Lett.
34
1693-1699
2012
-
-
1
-
1
-
8
1
-
1
-
2
-
4
-
-
1
-
-
-
-
-
2
-
2
-
1
-
2
-
-
2
-
-
-
-
-
1
2
-
1
-
-
8
-
1
-
1
-
2
-
-
-
1
-
-
-
-
2
-
2
-
1
-
2
-
-
-
-
1
1
-
-
-
723913
Akita
Highly stable meso-diaminopime ...
Ureibacillus thermosphaericus, Ureibacillus thermosphaericus A1
AMB Express
1
43
2011
-
-
1
-
-
-
6
-
-
-
2
4
-
4
-
-
1
-
-
-
1
-
6
1
1
-
2
-
1
-
1
1
-
-
-
-
-
1
1
-
-
-
-
6
-
-
-
-
2
4
-
-
-
1
-
-
1
-
6
1
1
-
2
-
1
-
1
-
-
-
-
-
-
-
712938
Kind
Systems-wide metabolic pathway ...
Corynebacterium glutamicum
Metab. Eng.
12
341-351
2010
-
-
1
-
1
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391524
Cirilli
The three-dimensional structur ...
Corynebacterium glutamicum, Lysinibacillus sphaericus
Protein Sci.
9
2034-2037
2000
-
-
-
1
-
-
1
-
-
-
-
-
-
5
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
2
1
-
-
-
-
-
2
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391522
Wang
Substrate binding and conforma ...
Corynebacterium glutamicum
Protein Sci.
7
293-299
1998
-
-
1
-
-
-
-
2
-
-
1
-
-
4
-
-
1
1
-
-
-
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
2
-
-
1
-
-
-
-
1
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391523
Scapin
Substrate and inhibitor bindin ...
Corynebacterium glutamicum
Biochemistry
37
3278-3285
1998
-
-
1
1
-
-
1
-
-
-
-
-
-
3
-
-
1
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
2
-
-
-
-
1
1
1
-
-
-
1
2
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391520
Scapin
Three-dimensional structure of ...
Corynebacterium glutamicum
Biochemistry
35
13540-13551
1996
-
-
1
1
-
-
-
-
-
-
-
-
-
5
-
-
1
1
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391521
Reddy
Expression, purification, and ...
Corynebacterium glutamicum
Proteins Struct. Funct. Genet.
25
514-516
1996
-
-
1
1
-
-
-
-
-
-
1
-
-
2
-
-
1
-
-
-
1
-
1
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
1
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
1
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2149
Abbott
-
Synthesis and testing of heter ...
Lysinibacillus sphaericus
J. Am. Chem. Soc.
116
6513-6520
1994
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
1
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2153
Chatterjee
Biosynthesis of lysine in plan ...
no activity in Chlamydomonas reinhardtii, no activity in Glycine max, no activity in Nicotiana tabacum, no activity in Zea mays
Plant Mol. Biol.
26
285-290
1994
-
-
-
-
-
-
-
-
-
-
-
-
-
9
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2145
Lam
Analogs of diaminopimelic acid ...
Lysinibacillus sphaericus
J. Biol. Chem.
263
11814-11819
1988
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4124
Yeh
General organization of the ge ...
Corynebacterium glutamicum, Corynebacterium glutamicum AS019
Mol. Gen. Genet.
212
105-111
1988
-
-
1
-
-
-
-
-
-
-
-
2
-
5
-
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
1
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
390193
Cremer
Regulation of enzymes of lysin ...
Corynebacterium glutamicum
J. Gen. Microbiol.
134
3221-3229
1988
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391502
Ishino
-
Cloning and sequencing of the ...
Corynebacterium glutamicum, Corynebacterium glutamicum RRL-5
Agric. Biol. Chem.
52
2903-2909
1988
-
-
1
-
-
-
-
-
-
-
1
2
-
2
-
-
-
-
-
-
2
-
4
1
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
-
2
-
4
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391504
Ishino
Nucleotide sequence of the mes ...
Corynebacterium glutamicum
Nucleic Acids Res.
15
3917
1987
-
-
1
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
390194
Bartlett
-
Regulation of the enzymes of l ...
Lysinibacillus sphaericus
J. Gen. Microbiol.
132
3169-3177
1986
-
-
-
-
-
-
3
-
-
-
-
1
-
1
-
-
-
-
-
-
3
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
3
-
-
-
-
-
1
-
-
-
-
-
-
3
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391505
Misono
-
Characterization of meso-diami ...
Achromobacter polymorph, Achromobacter superficialis, Agrobacterium tumefaciens, Alcaligenes viscolactis, Bacillus amyloliquefaciens, Bacillus cereus, Bacillus licheniformis, Bacterium mycoides, Brevibacillus brevis, Brevibacterium sp., Corynebacterium ammoniagenes, Corynebacterium glutamicum, Corynebacterium pseudodiphtheriticum, Enterobacter cloacae, Flavobacterium suaveolens, Glutamicibacter protophormiae, Hafnia alvei, Kocuria rosea, Lysinibacillus sphaericus, Micrococcus luteus, Morganella morganii, no activity in Escherichia coli, no activity in Klebsiella pneumoniae, no activity in Staphylococcus aureus, Providencia rettgeri, Pseudomonas aeruginosa, Pseudomonas alkanolytica, Pseudomonas chlororaphis subsp. aureofaciens, Pseudomonas cruciviae, Pseudomonas fragi, Pseudomonas putida, Terrabacter tumescens
Agric. Biol. Chem.
50
2729-2734
1986
-
-
-
-
-
-
22
9
-
-
3
8
-
32
-
-
1
-
-
-
1
2
37
3
-
-
2
-
2
-
1
31
2
-
-
-
-
-
31
-
-
-
-
22
2
9
-
-
3
8
-
-
-
1
-
-
1
2
37
3
-
-
2
-
2
-
1
-
-
-
-
-
-
-
391507
Misono
-
Purification and properties of ...
Brevibacterium sp., Brevibacterium sp. ICR 7000
Agric. Biol. Chem.
50
1329-1330
1986
-
-
-
-
-
-
5
8
-
-
2
2
-
2
-
-
1
-
-
-
1
-
4
1
-
-
1
-
2
-
1
2
-
-
-
-
-
-
2
-
-
-
-
5
-
8
-
-
2
2
-
-
-
1
-
-
1
-
4
1
-
-
1
-
2
-
1
-
-
-
-
-
-
-
2139
Bartlett
-
Species of Bacillus that make ...
Lysinibacillus sphaericus, Paenibacillus macerans, Sporosarcina globispora, Sporosarcina pasteurii
J. Gen. Microbiol.
131
2145-2152
1985
-
-
-
-
-
-
-
-
-
-
-
4
-
4
-
-
-
-
-
-
3
-
8
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
3
-
8
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391508
White
-
2,6-Diaminopimelate ...
Lysinibacillus sphaericus
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
8
377-383
1985
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
1
2
-
-
-
-
-
2
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
1
2
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
391510
Ishino
-
Involvement of meso-alpha,epsi ...
Corynebacterium glutamicum
Agric. Biol. Chem.
48
2257-2260
1984
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391511
White
-
The essential role of diaminop ...
Lysinibacillus sphaericus
J. Gen. Microbiol.
129
739-749
1983
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
2
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
391512
Misono
-
meso-alpha,epsilon-Diaminopime ...
Lysinibacillus sphaericus
Agric. Biol. Chem.
45
1455-1460
1981
-
-
-
-
-
-
6
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
6
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391513
Misono
Properties of meso-alpha,epsil ...
Lysinibacillus sphaericus
J. Biol. Chem.
255
10599-10605
1980
-
-
-
-
-
-
7
6
-
-
2
1
-
1
-
-
1
1
-
-
-
2
2
1
-
-
1
-
2
2
1
1
3
-
-
-
-
-
1
-
-
-
-
7
3
6
-
-
2
1
-
-
-
1
-
-
-
2
2
1
-
-
1
-
2
2
1
-
-
-
-
-
-
-
391514
Misono
-
Purification and properties of ...
Lysinibacillus sphaericus
Agric. Biol. Chem.
44
227-229
1980
-
-
-
-
-
-
-
3
-
-
1
1
-
1
-
-
1
-
-
-
1
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
3
-
-
1
1
-
-
-
1
-
-
1
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
391515
Misono
meso-alpha,epsilon-Diaminopime ...
Brevibacterium sp., Corynebacterium glutamicum, Erwinia aroidea, Lysinibacillus sphaericus, Proteus mirabilis, Proteus vulgaris, Pseudomonas fluorescens, Sarcina subflava
J. Bacteriol.
137
22-27
1979
-
-
-
-
-
-
-
-
-
-
-
4
-
8
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
8
-
-
-
-
-
-
8
-
-
-
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
12
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
391516
Misono
Occurrence of meso-alpha, epsi ...
Lysinibacillus sphaericus
Biochem. Biophys. Res. Commun.
72
89-93
1976
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
2
-
2
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
2
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-