Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Staphylococcus aureus |
Crystallization (Comment) | Organism |
---|---|
modeling of structure. HemQ enzymes lack the conserved arginine that is common to chlorite dismutases. A fully conserved tryptophan/tyrosine pair is buried deep in the active site cleft and fully conserved arginine residues at opposite ends of the distal pocket. A fully conserved glutamate residue is adjacent to the conserved tryptophan | Staphylococcus aureus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Fe-coproporphyrin III + 2 H2O2 | Staphylococcus aureus | - |
protoheme + 2 CO2 + 4 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus aureus | A0A0S3DY11 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Fe-coproporphyrin III + 2 H2O2 | - |
Staphylococcus aureus | protoheme + 2 CO2 + 4 H2O | - |
? |
General Information | Comment | Organism |
---|---|---|
physiological function | HemQ can stimulate the generation of protoporphyrin IX but not coproporphyrin III | Staphylococcus aureus |