Crystallization (Comment) | Organism |
---|---|
under strictly anaerobic conditions, comparison of the crystal structures of the three radical SAM enzymes HemN, BioB and MoaA show that the enzymes are structurally significantly different | Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe2+ | HemN binds a (4Fe-4S) cluster | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Cereibacter sphaeroides | - |
- |
- |
Cupriavidus necator | - |
- |
- |
Escherichia coli | - |
- |
- |
Salmonella enterica subsp. enterica serovar Typhimurium | - |
- |
- |
Purification (Comment) | Organism |
---|---|
by a single chromatographic step under anaerobic conditions | Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
coproporphyrinogen-III + S-adenosyl-L-methionine | - |
Escherichia coli | protoporphyrinogen IX + CO2 + L-methionine + 5'-deoxyadenosine | - |
? | |
coproporphyrinogen-III + S-adenosyl-L-methionine | - |
Cereibacter sphaeroides | protoporphyrinogen IX + CO2 + L-methionine + 5'-deoxyadenosine | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | by crystallographic studies | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
HemN | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
HemN | - |
Bacillus subtilis |
HemN | - |
Escherichia coli |
HemN | - |
Cereibacter sphaeroides |
HemN | - |
Cupriavidus necator |
oxygen-independent coproporphyrinogen III oxidase | - |
Salmonella enterica subsp. enterica serovar Typhimurium |
oxygen-independent coproporphyrinogen III oxidase | - |
Bacillus subtilis |
oxygen-independent coproporphyrinogen III oxidase | - |
Escherichia coli |
oxygen-independent coproporphyrinogen III oxidase | - |
Cereibacter sphaeroides |
oxygen-independent coproporphyrinogen III oxidase | - |
Cupriavidus necator |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Escherichia coli | |
S-adenosyl-L-methionine | HemN binds two SAM molecules | Escherichia coli |