Cloned (Comment) | Organism |
---|---|
SCAD DNA and amino acid sequence determination and analysis, the enzyme is encoded at 12q22-qter | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | subunits of the SCAD enzyme are synthesised in the cytosol as precursor proteins that are then imported into the mitochondrial matrix | Homo sapiens | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | subunits of the SCAD enzyme are synthesised in the cytosol as precursor proteins that are then imported into the mitochondrial matrix | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
SCAD | - |
Homo sapiens |
short-chain acylCoA dehydrogenase | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | SCAD functions in mitochondria and is involved in the beta-oxidation of fatty acyl-CoA compounds in chains of 4-6 carbons.The mitochondrial pathway of fatty acid beta-oxidation is an alternative source of energy, especially during stress or fasting | Homo sapiens |
additional information | patients with short-chain acyl-CoA dehydrogenase deficiency, a rare disorder of fatty acid oxidation, may show an increased risk of thyroid and other autoimmune diseases. The pathologic phenotype can include pernicious anaemia, vitiligo, autoimmune thyroiditis and lichen scleroatrophicus, overview | Homo sapiens |