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Literature summary for 1.3.8.1 extracted from

  • Dommes, V.; Kunau, W.H.
    Purification and properties of acyl coenzyme A dehydrogenases from bovine liver. Formation of 2-trans,4-cis-decadienoyl coenzyme A (1984), J. Biol. Chem., 259, 1789-1797.
    View publication on PubMed
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.009
-
 butyryl-CoA
-
 Bos taurus
0.02
-
 hexanoyl-CoA
-
 Bos taurus
0.032
-
 octanoyl-CoA
-
 Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40300
-
 4 * 40300, SDS-PAGE Bos taurus
188000
-
 gel filtration Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Bos taurus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.42
-
-
 Bos taurus
17.9
-
-
 Bos taurus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
butyryl-CoA + electron acceptor intermediate electron acceptors phenazine methosulfate or Meldola' s Blue (i.e. 8-dimethylamino-2,3-benzophenoxazinium chloride) Bos taurus 2-butenoyl-CoA + reduced acceptor
-
 ?
butyryl-CoA + electron acceptor terminal electron acceptor iodonitrotetrazolium chloride Bos taurus 2-butenoyl-CoA + reduced acceptor
-
 ?
hexanoyl-CoA + phenazine methosulfate + dichloroindophenol 52% of activity with butyryl-CoA Bos taurus 2-hexenoyl-CoA + reduced acceptor
-
 ?
octanoyl-CoA + Meldola's Blue + iodonitrotetrazolium chloride 14.4% of activity with butyryl-CoA Bos taurus 2-octenoyl-CoA + reduced acceptor
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 40300, SDS-PAGE Bos taurus