Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Geobacter metallireducens | |
Tungsten | required | Geobacter metallireducens | |
Zn2+ | required | Geobacter metallireducens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O | Geobacter metallireducens | - |
cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Geobacter metallireducens | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate = benzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O | reaction mechanism, quantum mechanical/molecular mechanical (QM/MM) calculations | Geobacter metallireducens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
benzoyl-CoA + reduced ferredoxin + 2 ATP + 2 H2O | - |
Geobacter metallireducens | cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 ADP + 2 phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tungsten-dependent benzoyl-coenzyme A reductase | - |
Geobacter metallireducens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Geobacter metallireducens | |
Ferredoxin | - |
Geobacter metallireducens |
General Information | Comment | Organism |
---|---|---|
additional information | rationalization of regioselectivity and predication of W vs Mo selectivity, analysis via quantum mechanical/molecular mechanical (QM/MM) calculations using the X-ray structure (PDB ID 4Z3Y, resolution of 2.36 A) of the tetrameric enzyme in complex with the benzoyl-CoA substrate, method optimization, overview | Geobacter metallireducens |